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3-Azido-2,3-dideoxy-1-O-(tert-butyldimethylsilyl)-β-D-arabino-hexopyranose

CAS 189454-43-1C12H25N3O4SiChemical Synthesis

3-Azido-2,3-dideoxy-1-O-(tert-butyldimethylsilyl)-β-D-arabino-hexopyranose (CAS: 189454-43-1) is a protected carbohydrate azide derivative with a molecular weight of 303.43 g/mol. This compound is valuable in carbohydrate chemistry for its azido group, which can be readily transformed into other functionalities. It is a key intermediate in the synthesis of complex carbohydrates, nucleoside analogues, and glycoconjugates, finding utility in chemical biology and synthetic chemistry research.

Synonyms
C12H25N3O4Si
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3-Azido-2,3-dideoxy-1-O-(tert-butyldimethylsilyl)-β-D-arabino-hexopyranose (C12H25N3O4Si) — chemical structure, CAS 189454-43-1; Chemistry, fine chemical supplied by Tech Serve Solutions
Carbohydrate AzidesCarbohydrate ChemistryCarbohydrate DerivativesChemical BiologyChemical Synthesis
01 /Applications

Synthesis of Modified Carbohydrates

Used as a building block in the synthesis of azido-deoxy sugars and other carbohydrate derivatives. The tert-butyldimethylsilyl protecting group allows for selective reactions and manipulations.

Nucleoside Analogue Development

Serves as a precursor in the creation of modified nucleosides and nucleoside analogues with potential antiviral or anticancer properties.

Glycoconjugate Chemistry

Facilitates the preparation of glycoconjugates through click chemistry or other coupling reactions, important for understanding biological processes.

Chemical Biology Research

Enables the introduction of azide functionalities into biological molecules for probing cellular pathways or developing diagnostic tools.

02 /Properties
Molecular weight303.43
Empirical formulaC12H25N3O4Si
Assay98%
Optical activity[α]20/D −32°, c = 1 in chloroform
Melting point73-75 °C(lit.)
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
189454-43-1
MDL number
MFCD01863611
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-Azido-2,3-dideoxy-1-O-(tert-butyldimethylsilyl)-β-D-arabino-hexopyranose used for?

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This compound is primarily used as a versatile intermediate in carbohydrate chemistry for the synthesis of modified sugars, nucleoside analogues, and glycoconjugates, particularly in research settings for chemical biology and drug discovery.

What is the CAS number and molecular formula for this product?

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The CAS number is 189454-43-1, and the empirical formula is C12H25N3O4Si.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this product with an assay of 98%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.

What are the safety and handling recommendations for this chemical?

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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany 3, indicating it is hazardous to water.

How is this chemical packed and shipped?

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Products are carefully packed and exported by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical compounds.

How can I request a quote or sample?

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To request a quote or sample, please contact our sales team through the website or by phone, providing the product name and CAS number.

Need 3-Azido-2,3-dideoxy-1-O-(tert-butyldimethylsilyl)-β-D-arabino-hexopyranose in a specific grade or volume?