2,5-Difluorobenzylzinc chloride solution
2,5-Difluorobenzylzinc chloride solution (CAS: 312692-89-0) is an organozinc halide offered by Tech Serve Solutions. With a molecular weight of 227.95 g/mol, this reagent is supplied as a 0.5 M solution in THF. It is valuable in organic synthesis for introducing the 2,5-difluorobenzyl group into various molecules, facilitating complex chemical transformations.
- Synonyms
- F2C6H3CH2ZnCl

Organic Synthesis Intermediate
Used as a key intermediate in the synthesis of complex organic molecules, particularly where selective introduction of a difluorobenzyl moiety is required.
Cross-Coupling Reactions
Serves as a nucleophilic coupling partner in various transition metal-catalyzed cross-coupling reactions, enabling the formation of new carbon-carbon bonds.
Pharmaceutical and Agrochemical Research
Applicable in the research and development of novel pharmaceutical agents and agrochemicals that incorporate fluorinated benzyl structures for enhanced properties.
| Molecular weight | 227.95 |
|---|---|
| Linear formula | F2C6H3CH2ZnCl |
| Boiling point | 65 °C |
| Density | 0.982 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |



Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Difluorobenzylzinc chloride solution used for?
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This solution is primarily used as a reagent in organic synthesis, particularly for introducing the 2,5-difluorobenzyl group through cross-coupling reactions and in the development of pharmaceuticals and agrochemicals.
What is the CAS number and formula for 2,5-Difluorobenzylzinc chloride solution?
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The CAS number is 312692-89-0, and the linear formula is F2C6H3CH2ZnCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. The specific assay is not detailed beyond its concentration. TSS does not represent this product as USP, BP, or EP grade.
How should 2,5-Difluorobenzylzinc chloride solution be handled safely?
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This solution is highly flammable (H225) and can form explosive peroxides. It is an irritant (H319, H335) and suspected of causing cancer (H351). Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources, and store at 2-8°C as it may form explosive peroxides.
How is 2,5-Difluorobenzylzinc chloride solution packed and shipped?
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The product is shipped under UN 2056, hazard class 3, packing group II, indicating it is a flammable liquid. It is exported by Tech Serve Solutions in quantities suitable for laboratory and industrial use.
How can I request a sample or quote for 2,5-Difluorobenzylzinc chloride solution?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number (312692-89-0).
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