Pimeloyl chloride
Pimeloyl chloride (CAS 142-79-0), with the linear formula ClCO(CH2)5COCl and a molecular weight of 197.06 g/mol, is a reactive acid halide. It serves as a valuable organic building block in chemical synthesis. Its bifunctional nature allows for participation in condensation and coupling reactions, leading to the formation of diverse organic structures, including polymers and macrocycles.
Preparation of Bis-acylureas
Pimeloyl chloride can be coupled with ureas to synthesise bis-acylureas, which are organic compounds with potential applications in various chemical research fields.
Synthesis of Antibody Production Precursors
It has been utilised in the preparation of triacetyl-15-pimelate-nivalenol, a compound essential for the development of antibodies targeted against nivalenol tetraacetate.
Formation of Macrocyclic Tetralactones
Through condensation reactions with stannoxane, pimeloyl chloride facilitates the formation of macrocyclic tetralactones, complex ring structures of interest in organic chemistry.
| Molecular weight | 197.06 |
|---|---|
| Linear formula | ClCO(CH2)5COCl |
| Assay | 98% |
| Boiling point | 113 °C/5 mmHg(lit.) |
| Density | 1.205 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.469(lit.) |
| Application | Pimeloyl chloride has been used in preparation of:• bis-acylureas, by the coupling reaction with ureas1• triacetyl-15-pimelate-nivalenol, required for production of antibody against nivalenol tetraacetate2• macrocyclic tetralactones, via condensation with stannoxane3 |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pimeloyl chloride used for?
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Pimeloyl chloride is used as a building block in chemical synthesis for applications such as the preparation of bis-acylureas, antibody production precursors, and macrocyclic tetralactones.
What is the CAS number and formula for Pimeloyl chloride?
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The CAS number for Pimeloyl chloride is 142-79-0, and its linear formula is ClCO(CH2)5COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pimeloyl chloride with an assay of 98%. This product is not represented as USP, BP, or EP grade.
How should Pimeloyl chloride be handled safely?
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Pimeloyl chloride is a hazardous substance that causes severe skin burns and eye damage and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a full-face respirator, gloves, and goggles. Ensure adequate ventilation.
How is Pimeloyl chloride packed and shipped?
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Pimeloyl chloride is shipped as a hazardous material, UN 3265, Class 8, Packing Group II. Specific packaging adheres to international shipping regulations for corrosive substances.
How can I request a quote or sample of Pimeloyl chloride?
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To request a quote or sample, please contact our sales team through the website or by phone, providing your contact details and the required quantity.
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