(S)-(+)-α-Methoxyphenylacetic acid
(S)-(+)-α-Methoxyphenylacetic acid (CAS: 26164-26-1; Formula: C6H5CH(OCH3)CO2H; Molar Mass: 166.17) is a chiral carboxylic acid offered by Tech Serve Solutions. This valuable building block is integral to asymmetric synthesis, finding application in the creation of complex organic molecules, including biologically active compounds and structural analogs. Its defined stereochemistry makes it crucial for enantioselective synthesis pathways in pharmaceutical and chemical research.
- IUPAC
- O-Methyl-L-mandelic acid
- Synonyms
- O-Methyl-L-mandelic acid
Synthesis of Biologically Active Molecules
This compound serves as a key reactant in synthesizing biologically active molecules such as acyclonucleoside phosphonates, structural analogs of adefovir, and labeled discodermolide for tubulin binding studies.
Chiral Building Block in Organic Synthesis
Its chiral nature makes it an important building block in organic synthesis, particularly for constructing molecules with specific stereochemical configurations required for pharmaceutical research and development.
Studies of Immunostimulating Chromanones
It is employed as a reactant in the study and synthesis of immunostimulating chromanones, including compounds like gonytolides A-C.
Reactant in Hydroxylation and Epoxidation Reactions
This acid is utilised as a reactant in various organic transformations, including hydroxylation and epoxidation reactions, contributing to the diversity of achievable molecular structures.
| Molecular weight | 166.17 |
|---|---|
| Linear formula | C6H5CH(OCH3)CO2H |
| Assay | 99% |
| Optical activity | [α]17/D +150°, c = 1 in ethanol |
| Application | Reactant involved in the synthesis of biologically active molecules including:• Acyclonucleoside phosphonates structural analogs of adefovir1• Labeled discodermolide for studying binding to tubulin2• 10-Isocyano-4-cadinene used for antifouling activity3Reactant involved in studies of immunostimulating chromanones gonytolides A-C4Reactant involved in: • Hydroxylations and epoxidations5• Hydrogenations6 |
| Melting point | 64-66 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-α-Methoxyphenylacetic acid used for?
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(S)-(+)-α-Methoxyphenylacetic acid is used as a reactant in the synthesis of biologically active molecules, including acyclonucleoside phosphonates and labeled discodermolide. It is also involved in studies of immunostimulating chromanones and reactions such as hydroxylations, epoxidations, and hydrogenations. It functions as a chiral building block and chiral resolving agent in asymmetric synthesis.
What is the CAS number and chemical formula for (S)-(+)-α-Methoxyphenylacetic acid?
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The CAS number is 26164-26-1 and the chemical formula is C6H5CH(OCH3)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-α-Methoxyphenylacetic acid with an assay of 99%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling recommendations for this product?
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This compound is a warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves. Ensure good ventilation.
How is (S)-(+)-α-Methoxyphenylacetic acid packaged, shipped, and exported?
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As a global supplier and exporter, Tech Serve Solutions packages and ships chemicals according to international regulations. Specific packaging details are available upon request for export orders.
How can I request a sample or quote for (S)-(+)-α-Methoxyphenylacetic acid?
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To request a sample or a quote, please contact our sales department through the TSS website or by phone. Please reference the product name and CAS number.
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