(S)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis(di-2-furylphosphine)
(S)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis(di-2-furylphosphine), CAS 145214-59-1, is a key atropisomeric phosphine ligand. With a molecular weight of 542.46 g/mol, it is crucial in asymmetric synthesis. This ligand, a member of the MeOBIPHEP family, facilitates highly enantioselective transformations, making it invaluable for producing chiral molecules in pharmaceutical and fine chemical research and development.
- IUPAC
- (S)-(−)-2,2′-Bis(di-2-furylphosphino)-6,6′-dimethoxy-1,1′-biphenyl,(S)-2-Furyl-MeOBIPHEP,SL-A108-2
- Synonyms
- 145214-59-1C30H24O6P2(S)-2-Furyl-MeOBIPHEPSL-A108-2
Asymmetric Catalysis
This ligand is widely employed in transition metal-catalyzed asymmetric reactions, enabling the synthesis of enantiomerically enriched products. Its unique atropisomeric structure imparts high stereoselectivity in various transformations.
Chiral Ligand Synthesis
It serves as a fundamental building block or catalyst in the synthesis of other complex chiral molecules and ligands. Its structure allows for fine-tuning of catalytic activity and selectivity.
Pharmaceutical Intermediate Production
The ability to control stereochemistry makes this compound essential for the development and production of chiral pharmaceutical intermediates, contributing to the efficient synthesis of enantiopure active pharmaceutical ingredients (APIs).
| Molecular weight | 542.46 |
|---|---|
| Empirical formula | C30H24O6P2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Application | Atropisomeric MeOBIPHEP ligands |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis(di-2-furylphosphine) used for?
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This compound is primarily used as an atropisomeric ligand in asymmetric catalysis for enantioselective synthesis, particularly in the production of chiral molecules for pharmaceuticals and fine chemicals.
What is the CAS number and molecular formula for this compound?
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The CAS number is 145214-59-1, and its empirical formula is C30H24O6P2, with a molecular weight of 542.46 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥97% and an optical purity of ee: ≥99%. It is supplied as a research or technical grade material and not as USP, BP, or EP.
What are the safety and handling considerations for this chemical?
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This chemical has a WGK Germany rating of 3. Recommended personal protective equipment includes eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used when handling.
How is this product packaged and shipped by TSS?
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Tech Serve Solutions reliably packs, ships, and exports chemicals globally, ensuring secure and compliant delivery to meet diverse customer needs worldwide.
How can I request a sample or quote for this product?
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To request a sample or a quote, please contact our sales team directly through our website or by phone, providing the product name and CAS number.
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