(S)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis(diisopropylphosphine)
(S)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis(diisopropylphosphine), also known as (S)-iPr-MeOBIPHEP, is a chiral phosphine ligand with the CAS number 150971-43-0 and a molecular weight of 446.54 g/mol. This atropisomeric compound is widely recognised for its effectiveness in asymmetric synthesis, serving as a key component in catalytic systems for producing enantiomerically pure compounds. It is particularly valuable in reactions requiring high stereoselectivity.
- IUPAC
- (S)-2,2′-Bis(diisopropylphosphino)-6,6′-dimethoxy-1,1′-biphenyl,(S)-iPr-MeOBIPHEP,SL-A116-2
- Synonyms
- 150971-43-0C26H40O2P2(S)-iPr-MeOBIPHEP(S)-2,2′-Bis(diisopropylphosphino)-6,6′-dimethoxy-1,1′-biphenylSL-A116-2

Asymmetric Catalysis
This ligand is employed in various asymmetric catalytic transformations, facilitating the stereoselective synthesis of chiral molecules. Its unique structure allows for precise control over reaction pathways, leading to high enantiomeric excesses in products.
Chiral Phosphine Ligand
As a member of the MeOBIPHEP ligand family, it is a critical reagent in homogeneous catalysis. It coordinates with transition metals to form active catalytic species essential for enantioselective reactions.
Pharmaceutical Intermediate Synthesis
The ability to produce enantiomerically pure compounds makes this ligand invaluable in the synthesis of pharmaceutical intermediates. It aids in constructing complex chiral drug molecules with the desired stereochemistry.
| Molecular weight | 446.54 |
|---|---|
| Empirical formula | C26H40O2P2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Application | Atropisomeric MeOBIPHEP ligands |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis(diisopropylphosphine) used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis and catalysis, particularly in reactions requiring high stereoselectivity, such as the synthesis of pharmaceutical intermediates.
What is the CAS number and formula for this chemical?
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The CAS number is 150971-43-0, and its empirical formula is C26H40O2P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥97% and an optical purity (ee) of ≥99%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for this compound?
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This compound is classified under WGK 3 in Germany. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter, should be used during handling to avoid exposure.
How is this product packed, shipped, and exported?
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Tech Serve Solutions expertly handles the packing, shipping, and global export of fine chemicals, ensuring compliance with all relevant regulations.
How can I request a sample or quote for this chemical?
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To request a sample or a quote, please use the contact form on our website or reach out to our sales team directly.
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