(S)-(4-Fluorophenyl)oxirane
(S)-(4-Fluorophenyl)oxirane (CAS 134356-74-4), with the molecular formula C8H7FO and a molecular weight of 138.14 g/mol, is a chiral epoxide. This fluorinated building block is instrumental in asymmetric synthesis. Its epoxide ring is reactive and can be opened stereoselectively, making it valuable for creating complex molecules with defined stereochemistry, particularly in pharmaceutical and fine chemical research.
- IUPAC
- (S)-4-Fluorostyrene oxide
- Synonyms
- (S)-4-Fluorostyrene oxide

Chiral Building Block in Organic Synthesis
Serves as a key intermediate in the stereoselective synthesis of chiral molecules. The epoxide functionality allows for controlled ring-opening reactions to introduce new stereocenters.
Fluorinated Compound Synthesis
Incorporates a fluorine atom and an epoxide moiety, enabling the synthesis of complex fluorinated organic compounds. These are of interest in medicinal chemistry and materials science.
Pharmaceutical Intermediate
Used in the development pathways of potential pharmaceutical agents where specific stereochemistry and fluorine substitution are desired for enhanced biological activity or pharmacokinetic properties.
Research and Development
A versatile reagent for academic and industrial research labs exploring novel synthetic routes and developing new chemical entities.
| Molecular weight | 138.14 |
|---|---|
| Empirical formula | C8H7FO |
| Assay | ≥95.0% (GC) |
| Optical purity | enantiomeric ratio: ≥99.0:1.0 |



Hazard statements
- H225Highly flammable liquid and vapour
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 22 °C / 71.6 °F |
| Transport (UN / ADR) | UN 1992 3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-21/22-36/37/38-40 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(4-Fluorophenyl)oxirane used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis and for the creation of complex fluorinated organic molecules, including potential pharmaceutical intermediates and research chemicals.
What are the CAS number and molecular formula of (S)-(4-Fluorophenyl)oxirane?
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(S)-(4-Fluorophenyl)oxirane has the CAS number 134356-74-4 and the molecular formula C8H7FO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(4-Fluorophenyl)oxirane with a minimum assay of 95.0% (GC) and an enantiomeric ratio of ≥99.0:1.0. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling (S)-(4-Fluorophenyl)oxirane?
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This compound is classified as Danger, with hazards including flammability (H225), acute toxicity (H301, H312), skin irritation (H315), eye irritation (H319), and potential carcinogenicity (H351). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., ABEK filter), is essential. Handle in a well-ventilated area, away from ignition sources.
Is (S)-(4-Fluorophenyl)oxirane exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (S)-(4-Fluorophenyl)oxirane, catering to international clients.
How can I request a sample or quote for (S)-(4-Fluorophenyl)oxirane?
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To request a sample or a quotation for (S)-(4-Fluorophenyl)oxirane, please contact the Tech Serve Solutions sales department through our website or by phone.
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