(S)-(+)-α-Hydroxy-1,3-dioxo-2-isoindolinebutyric acid
(S)-(+)-α-Hydroxy-1,3-dioxo-2-isoindolinebutyric acid (CAS 48172-10-7) is a chiral building block with the molecular formula C12H11NO5 and a molecular weight of 249.22 g/mol. This compound is valuable in asymmetric synthesis and heterocyclic chemistry. Its structure lends itself to applications requiring specific stereochemistry, making it a useful intermediate in the synthesis of complex organic molecules and pharmaceuticals. Available from TSS with an assay of 98%, it is suitable for research and chemical synthesis purposes.
- Synonyms
- C12H11NO5(S)-2-(1,3-Dioxo-2-isoindolinyl)-4-hydroxybutanoic acid
Asymmetric Synthesis
Serves as a chiral building block for constructing enantiomerically pure compounds. Its defined stereochemistry is crucial for synthesizing complex molecules with specific spatial arrangements, often required in pharmaceutical research and development.
Heterocyclic Chemistry
Utilised in the synthesis of various heterocyclic compounds. The isoindoline moiety within its structure can be incorporated into more complex fused or unfused heterocyclic systems, expanding its utility in medicinal chemistry and materials science.
Pharmaceutical Intermediates
Acts as a key intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its chiral nature is particularly important for developing drugs where stereoisomerism affects efficacy and safety.
Organic Synthesis Reagent
A versatile reagent in general organic synthesis, enabling chemists to introduce specific functional groups and stereocentres. It is employed in academic and industrial research laboratories for developing novel synthetic methodologies.
| Molecular weight | 249.22 |
|---|---|
| Empirical formula | C12H11NO5 |
| Assay | 98% |
| Optical activity | [α]20/D +6.5°, c = 1 in ethanol |
| Melting point | 157-159 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-α-Hydroxy-1,3-dioxo-2-isoindolinebutyric acid used for?
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(S)-(+)-α-Hydroxy-1,3-dioxo-2-isoindolinebutyric acid is primarily used as a chiral building block in asymmetric synthesis and heterocyclic chemistry, serving as an intermediate in the creation of complex organic molecules, including potential pharmaceutical agents.
What are the CAS number and chemical formula for (S)-(+)-α-Hydroxy-1,3-dioxo-2-isoindolinebutyric acid?
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The CAS number is 48172-10-7, and its empirical formula (Hill notation) is C12H11NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-α-Hydroxy-1,3-dioxo-2-isoindolinebutyric acid with an assay of 98%. This product is intended for research and chemical synthesis and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should (S)-(+)-α-Hydroxy-1,3-dioxo-2-isoindolinebutyric acid be handled safely?
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Handle with appropriate personal protective equipment: a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust, ensure adequate ventilation, and wash hands thoroughly after handling. It is classified as a Warning with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation).
How is this chemical exported and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product is carefully packaged and exported in compliance with international shipping regulations for chemical substances.
How can I request a sample or quote for (S)-(+)-α-Hydroxy-1,3-dioxo-2-isoindolinebutyric acid?
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To request a sample or a quote, please contact our sales team through the inquiry form on our website or by calling our main office. Please reference the product name and CAS number (48172-10-7) in your request.
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