(S)-(+)-sec-Butylamine
(S)-(+)-sec-Butylamine (CAS 513-49-5), with the chemical formula C2H5CH(NH2)CH3 and a molecular weight of 73.14 g/mol, is a chiral amine. It is a key building block in asymmetric synthesis and organic chemistry. Its specific stereochemistry makes it valuable for creating enantiomerically pure compounds, finding utility in the development of pharmaceuticals and fine chemicals. TSS supplies this high-purity reagent for advanced chemical research and manufacturing.
- IUPAC
- (S)-(+)-2-Aminobutane
- Synonyms
- (S)-(+)-2-Aminobutane

Chiral Auxiliary
As a chiral amine, (S)-(+)-sec-Butylamine can be employed as a chiral auxiliary in stereoselective reactions. It aids in controlling the stereochemical outcome of reactions, leading to the formation of specific enantiomers.
Building Block in Synthesis
This compound serves as a versatile chiral building block for the synthesis of more complex molecules. Its reactive amine group allows for various functionalisation pathways in organic synthesis.
Pharmaceutical Intermediate
Its chiral nature makes it an important intermediate in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs). This is crucial for drugs where specific stereoisomers exhibit desired therapeutic effects.
Ligand Synthesis
It can be used in the preparation of chiral ligands for asymmetric catalysis. These ligands are essential for promoting enantioselectivity in metal-catalyzed reactions.
| Molecular weight | 73.14 |
|---|---|
| Linear formula | C2H5CH(NH2)CH3 |
| Assay | 99% |
| Boiling point | 62.5 °C(lit.) |
| Density | 0.731 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.393(lit.) |
| Optical activity | [α]19/D +7.5°, neat |




Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
- H400Very toxic to aquatic life
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -9 °C / 15.8 °F |
| Transport (UN / ADR) | UN 2733 3/PG 2 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F,C,N |
| Risk statements (R) | 11-20/22-35-50 |
| Safety statements (S) | 9-16-26-28-36/37/39-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-sec-Butylamine used for?
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(S)-(+)-sec-Butylamine is primarily used as a chiral building block and auxiliary in asymmetric synthesis, particularly in the development of pharmaceuticals and fine chemicals due to its specific stereochemistry.
What is the CAS number and chemical formula for (S)-(+)-sec-Butylamine?
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The CAS number for (S)-(+)-sec-Butylamine is 513-49-5, and its chemical formula is C2H5CH(NH2)CH3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (S)-(+)-sec-Butylamine with an assay of 99%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should (S)-(+)-sec-Butylamine be handled safely?
+
(S)-(+)-sec-Butylamine is a highly flammable liquid and vapour (H225) that is harmful if swallowed (H302), causes severe skin burns and eye damage (H314), and is harmful if inhaled (H332). It is also very toxic to aquatic life (H400). Handle with appropriate personal protective equipment, including gloves, goggles, and respiratory protection, in a well-ventilated area, away from ignition sources.
How is (S)-(+)-sec-Butylamine packed and exported?
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Tech Serve Solutions professionally packs and exports (S)-(+)-sec-Butylamine, adhering to all relevant regulations for the safe transport of hazardous chemicals globally. Specific packaging details are available upon request.
How can I request a quote or sample for (S)-(+)-sec-Butylamine?
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To request a quote or sample for (S)-(+)-sec-Butylamine, please contact our sales team via the website or by phone, providing your specific requirements.
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