(S)-(+)-p-Toluenesulfinamide
(S)-(+)-p-Toluenesulfinamide (CAS: 188447-91-8), a chiral organic compound with the formula CH3C6H4S(O)NH2 and a molecular weight of 155.22 g/mol, is a valuable building block in organic synthesis. It is primarily employed in asymmetric synthesis due to its chiral nature, enabling the stereoselective formation of new chiral centres. This makes it a key intermediate for creating complex molecules with specific optical properties, particularly in pharmaceutical research and development.
Asymmetric Synthesis
This chiral sulfinamide serves as an effective chiral auxiliary and building block in asymmetric synthesis. It facilitates the stereoselective formation of carbon-carbon and carbon-heteroatom bonds, crucial for producing enantiomerically pure compounds.
Pharmaceutical Intermediates
Its ability to introduce chirality makes it a valuable intermediate in the synthesis of pharmacologically active molecules. It is used in the development pathways for new drug candidates where specific stereochemistry is critical for efficacy and safety.
Chiral Building Blocks
As an organic building block, it provides a readily accessible source of chirality. Researchers utilise it to construct complex chiral structures found in natural products and advanced organic materials.
| Molecular weight | 155.22 |
|---|---|
| Linear formula | CH3C6H4S(O)NH2 |
| Assay | 98% |
| Optical activity | [α]22/D +85°, c = 1 in chloroform |
| Melting point | 118-121 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-p-Toluenesulfinamide used for?
+
(S)-(+)-p-Toluenesulfinamide is primarily used as a chiral auxiliary and building block in asymmetric synthesis, particularly for the preparation of enantiomerically enriched compounds, and as an intermediate in pharmaceutical synthesis.
What is the CAS number and formula for (S)-(+)-p-Toluenesulfinamide?
+
The CAS number is 188447-91-8, and the chemical formula is CH3C6H4S(O)NH2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (S)-(+)-p-Toluenesulfinamide with a minimum assay of 98%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any pharmacopoeia grade.
How should (S)-(+)-p-Toluenesulfinamide be handled safely?
+
Handle with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter for protection against airborne particles. It carries a WGK Germany rating of 3, indicating a high hazard to water.
Does Tech Serve Solutions export (S)-(+)-p-Toluenesulfinamide?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (S)-(+)-p-Toluenesulfinamide, adhering to all relevant export regulations.
How can I request a quote or sample for (S)-(+)-p-Toluenesulfinamide?
+
To request a quote or sample, please contact our sales department via the website or direct inquiry, providing your specific requirements and contact information.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis