(S)-(+)-α-(Trifluoromethyl)benzyl alcohol
(S)-(+)-α-(Trifluoromethyl)benzyl alcohol (CAS: 340-06-7) is a chiral organic compound with the formula C6H5CH(CF3)OH and a molecular weight of 176.14 g/mol. This enantiomerically enriched alcohol is a valuable building block in asymmetric synthesis and a reagent for derivatization. It finds application in chemical synthesis and analysis, particularly where chiral resolution or specific stereochemical outcomes are required. TSS supplies this compound with a high assay for demanding chemical applications.
- IUPAC
- (+)-Phenyl(trifluoromethyl)carbinol,(S)-(+)-1-Phenyl-2,2,2-trifluoroethanol
- Synonyms
- (+)-Phenyl(trifluoromethyl)carbinol(S)-(+)-1-Phenyl-2,2,2-trifluoroethanol
Chiral Building Block in Asymmetric Synthesis
This enantiomerically pure alcohol serves as a crucial starting material or intermediate in the synthesis of complex chiral molecules. Its trifluoromethyl group and stereogenic center allow for precise control over stereochemistry in subsequent reactions.
Derivatization Reagent
It can be employed as a derivatization reagent, particularly in chromatography, to enhance the detectability or separability of analytes. The trifluoromethyl moiety can improve detection sensitivity in methods like HPLC.
Analytical Applications
The compound's defined chirality and chemical properties make it useful in analytical chemistry for developing chiral stationary phases or as a standard in stereochemical analysis.
Organic Synthesis Intermediate
Used in the broader field of organic synthesis, this compound facilitates the introduction of a chiral trifluoromethyl-substituted phenyl group into target molecules, contributing to the development of novel chemical entities.
| Molecular weight | 176.14 |
|---|---|
| Linear formula | C6H5CH(CF3)OH |
| Assay | ≥99.0% (sum of enantiomers, GC) |
| Grade | puriss. |
| Boiling point | 73-76 °C/9 mmHg(lit.) |
| Density | 1.3 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.462(lit.)n20/D 1.462 |
| Optical activity | [α]20/D 31.5±1.5°, neat |
| Optical purity | enantiomeric ratio: ≥98:2 (GC) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 84 °C / 183.2 °F |
| Transport (UN / ADR) | UN 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-α-(Trifluoromethyl)benzyl alcohol used for?
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(S)-(+)-α-(Trifluoromethyl)benzyl alcohol is primarily used as a chiral building block in asymmetric synthesis and as a derivatization reagent, particularly for analytical purposes like HPLC.
What is the CAS number and chemical formula for (S)-(+)-α-(Trifluoromethyl)benzyl alcohol?
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The CAS number is 340-06-7, and its chemical formula is C6H5CH(CF3)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical at a grade of 'puriss.' with an assay of ≥99.0% (sum of enantiomers, GC). We do not represent this product as USP, BP, or EP grade unless explicitly stated in the specifications.
How should (S)-(+)-α-(Trifluoromethyl)benzyl alcohol be handled safely?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be used. Ensure adequate ventilation and consult the Safety Data Sheet for detailed handling procedures.
How is (S)-(+)-α-(Trifluoromethyl)benzyl alcohol packed, shipped, and exported?
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Tech Serve Solutions expertly packs and ships fine chemicals, pharmaceutical intermediates, and laboratory reagents globally. Specific packaging details are available upon request, and all shipments comply with international regulations. We are a leading global supplier and exporter.
How can I request a sample or a quote for (S)-(+)-α-(Trifluoromethyl)benzyl alcohol?
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To request a sample or a quote, please contact our sales team through the website or by phone. Our representatives will assist you with your specific requirements.
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