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(S)-(+)-Tetrahydrofurfurylamine

CAS 7175-81-7C5H11NOChemical Synthesis

(S)-(+)-Tetrahydrofurfurylamine (CAS: 7175-81-7), with the molecular formula C5H11NO and a molecular weight of 101.15 g/mol, is a chiral amine building block. This optically active compound, exhibiting a specific rotation of +12° in chloroform, is valuable in asymmetric synthesis. Its furan and heterocyclic structure makes it a versatile intermediate in the creation of complex organic molecules for various chemical and pharmaceutical research applications.

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(S)-(+)-Tetrahydrofurfurylamine (C5H11NO) — chemical structure, CAS 7175-81-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksFuransHeterocyclic Building Blocks
01 /Applications

Chiral Building Block

As a chiral amine, (S)-(+)-Tetrahydrofurfurylamine serves as a fundamental component in the stereoselective synthesis of complex organic molecules. Its defined stereochemistry is crucial for constructing enantiomerically pure compounds.

Asymmetric Synthesis

This compound is employed in asymmetric synthesis, where its chirality can be used to induce stereoselectivity in reactions. It is a key intermediate for developing new chiral drugs and fine chemicals.

Heterocyclic Chemistry

The furan ring and amine functionality within (S)-(+)-Tetrahydrofurfurylamine make it a useful precursor in the synthesis of various heterocyclic compounds. These structures are prevalent in pharmaceuticals and materials science.

02 /Properties
Molecular weight101.15
Empirical formulaC5H11NO
Assay97%
Boiling point55 °C/18 mmHg(lit.)
Density0.98 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.455(lit.)
Optical activity[α]20/D +12°, c = 2 in chloroform
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H226Flammable liquid and vapour
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point46 °C / 114.8 °F
Transport (UN / ADR)UN 2943 3 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)10-36/37/38
Safety statements (S)16-26-36/37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
7175-81-7
MDL number
MFCD00085303
PubChem substance
24865834
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(+)-Tetrahydrofurfurylamine used for?

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(S)-(+)-Tetrahydrofurfurylamine is primarily used as a chiral building block in asymmetric synthesis and in the development of heterocyclic compounds for chemical and pharmaceutical research.

What are the CAS number and formula for (S)-(+)-Tetrahydrofurfurylamine?

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The CAS number for (S)-(+)-Tetrahydrofurfurylamine is 7175-81-7, and its molecular formula is C5H11NO.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (S)-(+)-Tetrahydrofurfurylamine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.

How should (S)-(+)-Tetrahydrofurfurylamine be handled safely?

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Handle with care, as (S)-(+)-Tetrahydrofurfurylamine is a flammable liquid and vapour (H226) and can cause skin (H315), eye (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be used, and it should be handled in a well-ventilated area, away from ignition sources.

Is (S)-(+)-Tetrahydrofurfurylamine subject to any controlled substance regulations?

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Based on the provided data, there is no indication that (S)-(+)-Tetrahydrofurfurylamine is a controlled substance.

How is (S)-(+)-Tetrahydrofurfurylamine shipped and exported?

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(S)-(+)-Tetrahydrofurfurylamine is shipped according to regulations for flammable liquids, with UN 2943 3 / PGIII classification. Tech Serve Solutions is experienced in global export.

How can I request a quote or sample?

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To request a quote or sample of (S)-(+)-Tetrahydrofurfurylamine, please contact our sales team through the website or by phone.

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