(S)-(+)-Pyrrolidine-3-carboxylic acid
(S)-(+)-Pyrrolidine-3-carboxylic acid (CAS: 72580-53-1; Formula: C5H9NO2; MW: 115.13) is a chiral beta-amino acid derivative. It is a valuable building block in organic synthesis, particularly in peptide chemistry and the development of unnatural amino acid analogues. This compound is supplied by Tech Serve Solutions with an assay of ≥98.0% (NT), suitable for research and chemical synthesis applications.
- IUPAC
- (S)-β-Proline

Chiral Building Block
Utilised in asymmetric synthesis to introduce stereochemical complexity into target molecules. Its pyrrolidine ring and carboxylic acid functionality make it a versatile starting material for complex organic scaffolds.
Peptide Chemistry
Incorporated into peptides to create novel structures with modified properties, such as enhanced stability or altered biological activity. Serves as an unnatural amino acid analogue in peptide research.
Chemical Biology Research
Employed in the design and synthesis of biologically relevant molecules. It can be used to probe protein-ligand interactions or develop new therapeutic agents.
Pharmaceutical Intermediate
Acts as a key intermediate in the synthesis pathways of various active pharmaceutical ingredients (APIs) where a chiral pyrrolidine motif is required.
| Molecular weight | 115.13 |
|---|---|
| Empirical formula | C5H9NO2 |
| Assay | ≥98.0% (NT) |
| Optical activity | [α]/D 20.0±2.0°, c = 2 in H2O |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-Pyrrolidine-3-carboxylic acid used for?
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(S)-(+)-Pyrrolidine-3-carboxylic acid is primarily used as a chiral building block in organic synthesis, particularly in peptide chemistry and for the development of unnatural amino acid derivatives and pharmaceutical intermediates.
What are the CAS number and formula for (S)-(+)-Pyrrolidine-3-carboxylic acid?
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The CAS number is 72580-53-1, and the empirical formula is C5H9NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-Pyrrolidine-3-carboxylic acid with an assay of ≥98.0% (NT). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety and handling recommendations for this product?
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Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter, should be used when handling. The product carries a WGK Germany rating of 3, indicating a high degree of hazard.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packaging and shipping details will be provided upon request, adhering to all relevant international regulations.
How can I request a sample or quote?
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To request a sample or a quotation for (S)-(+)-Pyrrolidine-3-carboxylic acid, please contact the Tech Serve Solutions sales team via the website or direct inquiry.
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