(S)-(+)-O-Acetylmandelic acid
(S)-(+)-O-Acetylmandelic acid (CAS: 7322-88-5) is a chiral carboxylic acid with the formula CH3CO2CH(C6H5)CO2H and a molecular weight of 194.18 g/mol. This compound serves as a valuable chiral derivatizing agent. It is particularly useful in NMR spectroscopy for determining the enantiomeric purity of various organic compounds, including alcohols, amines, and carboxylic acids, by forming diastereomeric derivatives.
- IUPAC
- (S)-(+)-α-Acetoxyphenylacetic acid
Chiral Derivatizing Agent
Utilised in asymmetric synthesis, (S)-(+)-O-Acetylmandelic acid is employed to derivatize other chiral molecules. This process aids in the NMR spectroscopic analysis for determining the enantiomeric purity of alcohols, amines, and carboxylic acids by creating diastereomeric species.
NMR Spectroscopy Reagent
This compound is a key reagent for NMR studies. Its ability to form distinct derivatives allows for the differentiation and quantification of enantiomers, providing critical data for chiral analysis in research and development.
Organic Synthesis Building Block
As a chiral building block, (S)-(+)-O-Acetylmandelic acid can be incorporated into more complex chiral molecules. Its defined stereochemistry makes it a useful starting material for stereoselective synthesis pathways.
| Molecular weight | 194.18 |
|---|---|
| Linear formula | CH3CO2CH(C6H5)CO2H |
| Assay | 99% |
| Optical activity | [α]28/D +153°, c = 2 in acetone |
| Optical purity | ee: 98% (GLC) |
| Application | The (R)- and (S)-isomers are chiral derivatizing agents for NMR determination of enantiomeric purity of α-deuterated carboxylic acids, alcohols, and amines.1 |
| Melting point | 97-99 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-O-Acetylmandelic acid used for?
+
(S)-(+)-O-Acetylmandelic acid is primarily used as a chiral derivatizing agent for the NMR spectroscopic determination of enantiomeric purity of α-deuterated carboxylic acids, alcohols, and amines.
What are the CAS number and chemical formula for (S)-(+)-O-Acetylmandelic acid?
+
The CAS number for (S)-(+)-O-Acetylmandelic acid is 7322-88-5, and its chemical formula is CH3CO2CH(C6H5)CO2H.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (S)-(+)-O-Acetylmandelic acid with a minimum assay of 99%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling (S)-(+)-O-Acetylmandelic acid?
+
Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary. The compound is classified with WGK Germany 3, indicating a high hazard to water.
How is (S)-(+)-O-Acetylmandelic acid packaged and exported?
+
Tech Serve Solutions expertly packages and exports fine chemicals globally, adhering to stringent international shipping regulations to ensure safe and compliant delivery.
How can I request a quote or sample for (S)-(+)-O-Acetylmandelic acid?
+
Please contact our sales team or use the online inquiry form to request a quote or a sample of (S)-(+)-O-Acetylmandelic acid.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis