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(S)-(+)-N-Boc-3-pyrrolidinol

CAS 101469-92-5C9H17NO3Chemical Synthesis

(S)-(+)-N-Boc-3-pyrrolidinol (CAS: 101469-92-5, Formula: C9H17NO3) is a chiral heterocyclic compound with a molecular weight of 187.24 g/mol. As a protected pyrrolidine derivative, it serves as a valuable building block in organic synthesis. Its primary documented application is in the synthesis of ligands for nicotinic acetylcholine receptors, highlighting its utility in pharmaceutical research and development. Tech Serve Solutions provides this chemical with an assay of 97%.

IUPAC
(S)-N-(tert-Butoxycarbonyl)-(+)-3-pyrrolidinol
Synonyms
(S)-N-(tert-Butoxycarbonyl)-(+)-3-pyrrolidinol
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(S)-(+)-N-Boc-3-pyrrolidinol (C9H17NO3) — chemical structure, CAS 101469-92-5; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksPyrrolidines
01 /Applications

Ligand Synthesis for Nicotinic Acetylcholine Receptors

This compound is utilised in the synthesis of specific ligands designed to interact with nicotinic acetylcholine receptors. This application is significant in neuroscience and drug discovery, particularly for conditions affecting the central nervous system.

Chiral Building Block in Organic Synthesis

As a chiral pyrrolidine derivative, (S)-(+)-N-Boc-3-pyrrolidinol acts as a versatile building block for constructing complex organic molecules. Its stereochemistry is crucial for developing enantiomerically pure target compounds.

Heterocyclic Chemistry Intermediate

This molecule is an important intermediate in heterocyclic chemistry, offering a functionalised pyrrolidine ring that can be further modified. It facilitates the introduction of chiral pyrrolidine motifs into larger molecular structures.

02 /Properties
Molecular weight187.24
Empirical formulaC9H17NO3
Assay97%
Optical activity[α]20/D +26°, c = 1% in methanol
ApplicationUsed in synthesis of ligands for the nicotinic acetylcholine receptor.1
Melting point60-64 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H301Toxic if swallowed
  • H315Causes skin irritation
  • H318Causes serious eye damage
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P301IF SWALLOWED
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)T
Risk statements (R)25-37/38-41
Safety statements (S)26-39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
101469-92-5
MDL number
MFCD01317839
PubChem substance
24882649
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(+)-N-Boc-3-pyrrolidinol used for?

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(S)-(+)-N-Boc-3-pyrrolidinol is primarily used in organic synthesis, notably for preparing ligands targeting nicotinic acetylcholine receptors. It also serves as a chiral building block in the construction of complex organic molecules.

What are the CAS number and formula for (S)-(+)-N-Boc-3-pyrrolidinol?

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The CAS number for (S)-(+)-N-Boc-3-pyrrolidinol is 101469-92-5, and its molecular formula is C9H17NO3.

What grade and purity does Tech Serve Solutions supply for (S)-(+)-N-Boc-3-pyrrolidinol?

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Tech Serve Solutions supplies (S)-(+)-N-Boc-3-pyrrolidinol with an assay of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.

How should (S)-(+)-N-Boc-3-pyrrolidinol be handled safely?

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Handling requires caution due to its hazards (H301, H315, H318, H335). Use appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator. Ensure adequate ventilation and avoid ingestion, skin contact, and inhalation. It is classified as Danger, indicating significant acute toxicity and corrosive properties.

How is (S)-(+)-N-Boc-3-pyrrolidinol packed and exported?

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(S)-(+)-N-Boc-3-pyrrolidinol is packed according to international shipping regulations for hazardous materials (UN 2811, Class 6.1, Packing Group III). Tech Serve Solutions is experienced in exporting chemicals globally.

How can I request a sample or quote for (S)-(+)-N-Boc-3-pyrrolidinol?

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To request a sample or obtain a quote for (S)-(+)-N-Boc-3-pyrrolidinol, please contact our sales team through the website or by phone, providing your specific requirements and delivery details.

Need (S)-(+)-N-Boc-3-pyrrolidinol in a specific grade or volume?