(S)-(+)-N-(Boc)-2-methylpiperidine
(S)-(+)-N-(Boc)-2-methylpiperidine (CAS: 183903-99-3, C11H21NO2) is a chiral heterocyclic building block with a molecular weight of 199.29 g/mol. It is valuable in asymmetric synthesis and chemical research. This compound, with a refractive index of n20/D 1.453 and a boiling point of 54-56 °C/0.05 mmHg, offers a specific stereochemical configuration for creating complex molecules. Its defined optical activity and purity make it a reliable reagent for advanced chemical synthesis.
- IUPAC
- (S)-(+)-N-tert-(Butoxycarbonyl)-2-methylpiperidine

Asymmetric Synthesis
Serves as a chiral building block in the stereoselective synthesis of complex organic molecules, enabling the creation of enantiomerically pure compounds.
Pharmaceutical Intermediate
Used in the development of active pharmaceutical ingredients (APIs) where specific stereochemistry is critical for biological activity and efficacy.
Chemical Research
A versatile reagent for academic and industrial research laboratories exploring novel synthetic routes and chemical transformations.
Heterocyclic Chemistry
Its piperidine core makes it useful for constructing substituted heterocyclic systems found in various biologically active compounds.
| Molecular weight | 199.29 |
|---|---|
| Empirical formula | C11H21NO2 |
| Assay | 98% |
| Boiling point | 54-56 °C/0.05 mmHg(lit.) |
| Density | 0.937 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.453(lit.) |
| Optical activity | [α]20/D +46°, c = 1 in chloroform |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 101 °C / 213.8 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-N-(Boc)-2-methylpiperidine used for?
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(S)-(+)-N-(Boc)-2-methylpiperidine is primarily used as a chiral building block in asymmetric synthesis, particularly for creating complex organic molecules and pharmaceutical intermediates where specific stereochemistry is essential.
What is the CAS number and formula for (S)-(+)-N-(Boc)-2-methylpiperidine?
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The CAS number is 183903-99-3, and its empirical formula is C11H21NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-N-(Boc)-2-methylpiperidine with an assay of 98%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated otherwise in the product specifications.
What are the safety considerations when handling this compound?
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This compound is classified with a GHS07 symbol and a Warning signal word, with hazard statements including H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, such as eyeshields, gloves, and suitable respiratory protection, should be used. Handle in a well-ventilated area.
How is this chemical packed and exported?
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Tech Serve Solutions packs and exports (S)-(+)-N-(Boc)-2-methylpiperidine according to international shipping regulations for chemicals, ensuring safe transit to global destinations.
How can I request a quote or sample?
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To request a quote or sample of (S)-(+)-N-(Boc)-2-methylpiperidine, please contact our sales team through the website or by phone, providing your specific requirements.
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