(S)-(+)-Mandelic acid
(S)-(+)-Mandelic acid (CAS: 17199-29-0), with the chemical formula C6H5CH(OH)CO2H and a molecular weight of 152.15 g/mol, is a chiral carboxylic acid. It is recognised for its utility as a versatile reagent in asymmetric synthesis. This compound plays a key role in the resolution of racemic mixtures and is employed in the preparation of various amides, making it valuable for fine chemical and pharmaceutical intermediate synthesis.
- IUPAC
- (S)-α-Hydroxyphenylacetic acid
- Synonyms
- (S)-Mandelic acid(S)-2-Hydroxy-2-phenylacetic acid(S)-(+)-2-Hydroxy-2-phenylacetic acid
Resolution of Racemates
(S)-(+)-Mandelic acid is a well-established chiral resolving agent. It selectively forms diastereomeric salts with racemic mixtures, enabling the separation of enantiomers.
Preparation of Amides
This chiral acid serves as a precursor in the synthesis of optically active amides. These amides are valuable intermediates in the production of pharmaceuticals and other complex organic molecules.
Chiral Building Block
As a chiral building block, (S)-(+)-Mandelic acid offers a defined stereogenic centre for the construction of more complex chiral molecules in asymmetric synthesis.
| Molecular weight | 152.15 |
|---|---|
| Linear formula | C6H5CH(OH)CO2H |
| Assay | ≥99% |
| Grade | ReagentPlus® |
| Optical activity | [α]20/D +154°, c = 2.8 in H2O |
| Optical purity | ee: 99% (GLC) |
| Application | A versatile reagent1 used in the resolution of racemates2 and the preparation of amides.3,4,5 |
| Melting point | 131-134 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-Mandelic acid used for?
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(S)-(+)-Mandelic acid is primarily used as a chiral resolving agent for separating racemic mixtures and in the synthesis of amides and other chiral compounds.
What is the CAS number and chemical formula for (S)-(+)-Mandelic acid?
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The CAS number is 17199-29-0, and the chemical formula is C6H5CH(OH)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-Mandelic acid with an assay of ≥99% and a grade of ReagentPlus®. We do not represent this product as USP, BP, or EP grade.
How should (S)-(+)-Mandelic acid be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for detailed information.
Does TSS export (S)-(+)-Mandelic acid?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (S)-(+)-Mandelic acid.
How can I request a quote or sample?
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Please contact our sales department through the website to request a quote or a sample of (S)-(+)-Mandelic acid.
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