(S)-(+)-Ketoprofen
(S)-(+)-Ketoprofen (CAS: 22161-81-5) is a chiral carboxylic acid with the molecular formula C<sub>6</sub>H<sub>5</sub>COC<sub>6</sub>H<sub>4</sub>CH(CH<sub>3</sub>)CO<sub>2</sub>H and a molecular weight of 254.28 g/mol. This enantiomerically pure compound is valuable in asymmetric synthesis and serves as a key building block in organic chemistry. Its specific optical activity, [α]22/D +49° in methanol, highlights its defined stereochemistry, making it suitable for stereoselective chemical transformations and research in bioactive small molecules.
- IUPAC
- (S)-(+)-3-Benzoyl-α-methylbenzeneacetic acid,(S)-2-(3-Benzoylphenyl)propionic acid
- Synonyms
- (S)-2-(3-Benzoylphenyl)propionic acid(S)-3-Benzoyl-α-methylbenzeneacetic acid
Chiral Building Block
(S)-(+)-Ketoprofen is utilised as a chiral building block in the synthesis of more complex stereochemically defined molecules. Its established configuration is crucial for stereoselective reactions in organic synthesis.
Asymmetric Synthesis
This compound is a valuable tool in asymmetric synthesis, enabling chemists to create enantiomerically pure products. It is often employed in research settings focusing on stereoselective chemical transformations.
Bioactive Small Molecule Research
As a bioactive small molecule, (S)-(+)-Ketoprofen finds application in research exploring biological pathways and targets. Its specific structure and chirality are important for interactions at the molecular level.
Carboxylic Acid Derivative
The carboxylic acid functionality of (S)-(+)-Ketoprofen allows for various chemical modifications and conjugations. This makes it useful for derivatisation in medicinal chemistry and materials science.
| Molecular weight | 254.28 |
|---|---|
| Linear formula | C6H5COC6H4CH(CH3)CO2H |
| Assay | 99% |
| Optical activity | [α]22/D +49°, c = 1 in methanol |
| Melting point | 75-78 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-50/53 |
| Safety statements (S) | 26-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... IL8RA(3577), PTGS1(5742), PTGS2(5743)mouse ... Ptgs2(19225) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-Ketoprofen used for?
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(S)-(+)-Ketoprofen is used as a chiral building block and a tool in asymmetric synthesis, particularly in the research of bioactive small molecules and as a carboxylic acid derivative for further chemical modification.
What are the CAS number and molecular formula for (S)-(+)-Ketoprofen?
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The CAS number for (S)-(+)-Ketoprofen is 22161-81-5, and its molecular formula is C6H5COC6H4CH(CH3)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-Ketoprofen with an assay of 99%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.
How should (S)-(+)-Ketoprofen be handled safely?
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(S)-(+)-Ketoprofen is a hazardous substance. Handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, faceshields, and gloves. Avoid dust formation and breathing vapours. It is toxic if swallowed, causes skin irritation, and serious eye irritation.
How is (S)-(+)-Ketoprofen shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. (S)-(+)-Ketoprofen is shipped and exported in accordance with international regulations for hazardous materials, identified under UN 2811 with hazard class 6.1.
How can I request a sample or quote for (S)-(+)-Ketoprofen?
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To request a sample or a quote for (S)-(+)-Ketoprofen, please contact the Tech Serve Solutions sales team through the website or by phone, providing your specific requirements.
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