(S)-(+)-Leucinol
(S)-(+)-Leucinol (CAS: 7533-40-6) is a chiral amino alcohol with the molecular formula (CH₃)₂CHCH₂CH(NH₂)CH₂OH and a molecular weight of 117.19 g/mol. This compound serves as a valuable chiral building block in organic synthesis. It is primarily utilised as a starting material for the development of inhibitors targeting enzymes like aminopeptidase N and phospholipase A₂. Tech Serve Solutions provides this reagent for research and development purposes.
- IUPAC
- (S)-2-Amino-4-methyl-1-pentanol,2-Amino-4-methyl-1-pentanol,L-Leucinol
- Synonyms
- (S)-2-Amino-4-methyl-1-pentanolL-Leucinol
Synthesis of Aminopeptidase N Inhibitors
(S)-(+)-Leucinol is a key starting material for the synthesis of potent aminopeptidase N inhibitors. These inhibitors have potential applications in various therapeutic areas.
Development of Phospholipase A₂ Inhibitors
This chiral amino alcohol is employed in the synthetic routes for developing phospholipase A₂ inhibitors. Such compounds are of interest in the study and treatment of inflammatory conditions.
Chiral Building Block in Organic Synthesis
As a readily available chiral synthon, (S)-(+)-Leucinol is instrumental in constructing complex chiral molecules for pharmaceutical research and chemical biology.
| Molecular weight | 117.19 |
|---|---|
| Linear formula | (CH3)2CHCH2CH(NH2)CH2OH |
| Assay | 96% |
| Boiling point | 198-200 °C/768 mmHg(lit.) |
| Density | 0.917 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4511(lit.) |
| Optical activity | [α]20/D +4°, c = 9 in ethanol |
| Optical purity | ee: 99% (GLC) |
| Application | Starting material for the synthesis of aminopeptidase N1 and phospholipase A22 inhibitors. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 91 °C / 195.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-Leucinol primarily used for?
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Tech Serve Solutions supplies (S)-(+)-Leucinol as a starting material for the synthesis of aminopeptidase N and phospholipase A₂ inhibitors, and as a chiral building block in organic synthesis.
What is the CAS number and formula for (S)-(+)-Leucinol?
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The CAS number for (S)-(+)-Leucinol is 7533-40-6, and its linear formula is (CH₃)₂CHCH₂CH(NH₂)CH₂OH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (S)-(+)-Leucinol with a minimum assay of 96%. This product is intended for research and development use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should (S)-(+)-Leucinol be handled safely?
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(S)-(+)-Leucinol is classified as a warning substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be worn. Ensure adequate ventilation or use a suitable respirator.
How is (S)-(+)-Leucinol packed and exported?
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Tech Serve Solutions ensures secure and compliant packaging for domestic and international export of (S)-(+)-Leucinol, adhering to all relevant transportation regulations (NA 1993 / PGIII).
How can I request a sample or quote for (S)-(+)-Leucinol?
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To request a sample or a quotation for (S)-(+)-Leucinol, please contact our sales department through the TSS website or by phone.
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