Tetramethylammonium triacetoxyborohydride
Tetramethylammonium triacetoxyborohydride (CAS 109704-53-2) is a selective reducing agent primarily employed in organic synthesis. Its chemical formula is (CH3)4N(CH3CO2)3BH, with a molecular weight of 263.10 g/mol. This compound is valued for its ability to perform mild reductions of various functional groups. It serves as a key reagent in the synthesis of complex organic molecules and pharmaceutical intermediates, offering a controlled alternative to stronger borohydride reagents.
Selective Reductions in Organic Synthesis
Tetramethylammonium triacetoxyborohydride is utilised for the selective reduction of aldehydes and ketones to alcohols under mild conditions. It is also effective for the reductive amination of imines and carbonyl compounds, forming amines.
Pharmaceutical Intermediate Synthesis
This reagent is instrumental in multi-step syntheses within the pharmaceutical industry, facilitating the precise modification of molecular structures to produce active pharmaceutical ingredients (APIs) and their precursors.
Preparation of Specialty Chemicals
Its controlled reactivity makes it suitable for the synthesis of fine and specialty chemicals where specific functional group transformations are required without affecting other sensitive parts of the molecule.
| Molecular weight | 263.10 |
|---|---|
| Linear formula | (CH3)4N(CH3CO2)3BH |
| Assay | 95% |
| Grade | purum |
| Melting point | 93-98 °C(lit.) |
Hazard statements
- H261In contact with water releases flammable gas
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P422
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2813 4.3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 15-36/37/38 |
| Safety statements (S) | 26-36-43 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetramethylammonium triacetoxyborohydride used for?
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Tetramethylammonium triacetoxyborohydride is a selective reducing agent used in organic synthesis for the reduction of aldehydes, ketones, and imines, and for the synthesis of pharmaceutical intermediates and specialty chemicals.
What are the CAS number and formula for Tetramethylammonium triacetoxyborohydride?
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The CAS number is 109704-53-2, and its linear formula is (CH3)4N(CH3CO2)3BH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetramethylammonium triacetoxyborohydride in 'purum' grade with an assay of 95%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Tetramethylammonium triacetoxyborohydride be handled safely?
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This compound is flammable and irritating. Handle with appropriate personal protective equipment, including eyeshields and gloves, in a well-ventilated area. Avoid contact with skin and eyes, and avoid breathing dust. Reacts with water, releasing flammable gas.
Is Tetramethylammonium triacetoxyborohydride shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Tetramethylammonium triacetoxyborohydride, and can facilitate international shipments.
How can I request a quote or sample?
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To request a quote or sample of Tetramethylammonium triacetoxyborohydride, please contact our sales team through the website or by phone, providing your specific requirements.
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