1-Amino-4-methylpiperazine
1-Amino-4-methylpiperazine (CAS 6928-85-4, C5H13N3) is a versatile heterocyclic building block with a molecular weight of 115.18 g/mol. It is primarily utilised in chemical synthesis, including the preparation of pyrazolo-pyrazine and pyridine derivatives. This compound also functions as a solvating and stabilising agent in nanoparticle synthesis. Available from Tech Serve Solutions, it offers a reliable option for research and industrial applications.

Synthesis of Heterocyclic Compounds
1-Amino-4-methylpiperazine serves as a key intermediate in the synthesis of complex heterocyclic structures such as pyrazolo-pyrazine and pyridine derivatives, facilitating the development of novel chemical entities.
Nanoparticle Preparation
This amine acts as an effective solvating and stabilising agent, aiding in the preparation of uniform silver nanoparticles with controlled sizes, typically below 10nm.
Organic Synthesis Intermediate
As a difunctional molecule, it is valuable in various organic synthesis pathways for creating more complex molecules and functional materials.
| Molecular weight | 115.18 |
|---|---|
| Empirical formula | C5H13N3 |
| Assay | 97% |
| Boiling point | 172-175 °C(lit.) |
| Density | 0.957 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.485(lit.) |
| Solubility | water: soluble |
| Application | 1-Amino-4-methylpiperazine has been used:• in synthesis of pyrazolo-pyrazine, -pyridine derivatives1 and 2-[(4-methylpiperazin-1-yl)iminomethyl]phenol2• as a solvating and stabilizing agent in the preparation of uniform Ag nanoparticles (3 |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 63 °C / 145.4 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Amino-4-methylpiperazine used for?
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1-Amino-4-methylpiperazine is used in the synthesis of pyrazolo-pyrazine and pyridine derivatives, and as a solvating and stabilising agent in the preparation of silver nanoparticles.
What are the CAS number and formula for 1-Amino-4-methylpiperazine?
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The CAS number for 1-Amino-4-methylpiperazine is 6928-85-4, and its molecular formula is C5H13N3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Amino-4-methylpiperazine with a minimum purity of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 1-Amino-4-methylpiperazine be handled safely?
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1-Amino-4-methylpiperazine is classified with Warning signal word and carries hazard statements H302, H312, H315, H319, H332, and H335. Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, must be used. Ensure good ventilation.
Can Tech Serve Solutions export 1-Amino-4-methylpiperazine globally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1-Amino-4-methylpiperazine.
How can I request a quote or sample for 1-Amino-4-methylpiperazine?
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To request a quote or sample for 1-Amino-4-methylpiperazine, please contact our sales team via the website or directly by phone.
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