3,4-Difluorobenzylamine
3,4-Difluorobenzylamine (CAS 72235-53-1) is a fluorinated organic building block with a molecular weight of 143.13 g/mol. This compound, also represented by the linear formula F₂C₆H₃CH₂NH₂, is primarily utilised in chemical synthesis. Its specific structural features make it a valuable intermediate in the development of novel chemical entities, particularly within the pharmaceutical and agrochemical research sectors. Tech Serve Solutions supplies this chemical at a standard assay of 98%.
- Synonyms
- F2C6H3CH2NH2
Pharmaceutical Intermediate
3,4-Difluorobenzylamine serves as a key building block in the synthesis of complex organic molecules. It has been documented for its use in preparing specific pharmacologically relevant compounds, such as derivatives of pentenamide.
Agrochemical Research
The difluorobenzyl moiety is incorporated into various structures during the discovery phase of new agrochemicals. Its presence can influence the biological activity and physicochemical properties of candidate molecules.
Organic Synthesis
As a versatile amine, this compound is employed in a range of organic transformations, including nucleophilic substitutions and amide formations, contributing to the construction of diverse chemical architectures.
| Molecular weight | 143.13 |
|---|---|
| Linear formula | F2C6H3CH2NH2 |
| Assay | 98% |
| Density | 1.21 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.493(lit.) |
| Application | 3,4-Difluorobenzylamine has been used in the preparation of 2-[(5-chloro-2-methoxyphenyl)sulfonyl(2-fluoroallyl)amino]-N-(3,4-difluorobenzyl)-4-pentenamide1. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 79 °C / 174.2 °F |
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Difluorobenzylamine used for?
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3,4-Difluorobenzylamine is primarily used as a building block in organic synthesis, particularly for the preparation of pharmaceutical intermediates and in agrochemical research.
What is the CAS number and formula for 3,4-Difluorobenzylamine?
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The CAS number is 72235-53-1 and the linear formula is F₂C₆H₃CH₂NH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-Difluorobenzylamine with an assay of 98%. We do not represent this product as USP, BP, EP or any other pharmacopoeia grade unless explicitly stated in the product data.
How should 3,4-Difluorobenzylamine be handled safely?
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3,4-Difluorobenzylamine is classified as corrosive (H314). Handling requires appropriate personal protective equipment including gloves, goggles, a face shield, and suitable respiratory protection (e.g., type ABEK filter). It should be handled with extreme care to avoid skin and eye contact.
Is 3,4-Difluorobenzylamine available for international export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3,4-Difluorobenzylamine, fulfilling orders worldwide.
How can I request a quote or sample for 3,4-Difluorobenzylamine?
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To request a quote or sample, please contact our sales team through the provided channels on the Tech Serve Solutions website, specifying the product name and CAS number.
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