3,4-Difluorobenzylzinc bromide solution
3,4-Difluorobenzylzinc bromide solution (CAS: 307496-34-0) is an organozinc halide reagent supplied by Tech Serve Solutions. With a molecular weight of 272.41 g/mol and a concentration of 0.5 M in THF, this compound is a valuable tool in organic synthesis. It is primarily utilised in cross-coupling reactions and as a nucleophilic source of the 3,4-difluorobenzyl group for introducing this moiety into various organic molecules.
- Synonyms
- F2C6H3CH2ZnBr
Organic Synthesis Reagent
This organozinc bromide serves as a versatile reagent in organic synthesis, particularly for the introduction of the 3,4-difluorobenzyl group into complex molecules. Its utility is prominent in forming new carbon-carbon bonds.
Cross-Coupling Reactions
It is employed in various transition-metal-catalysed cross-coupling reactions, such as Negishi couplings. These reactions are fundamental for building molecular complexity in the synthesis of pharmaceuticals and advanced materials.
Fluorinated Building Block
As a source of a difluorinated benzyl moiety, it is instrumental in the synthesis of fluorinated organic compounds, which are increasingly important in medicinal chemistry and materials science due to their unique electronic properties.
| Molecular weight | 272.41 |
|---|---|
| Linear formula | F2C6H3CH2ZnBr |
| Density | 0.98 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H261In contact with water releases flammable gas
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
- P422
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Difluorobenzylzinc bromide solution used for?
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3,4-Difluorobenzylzinc bromide solution is used as a reagent in organic synthesis, particularly for introducing the 3,4-difluorobenzyl group via cross-coupling reactions like Negishi coupling.
What are the CAS number and formula for this product?
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The CAS number for 3,4-Difluorobenzylzinc bromide solution is 307496-34-0, and its linear formula is F2C6H3CH2ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-Difluorobenzylzinc bromide solution at a concentration of 0.5 M in THF. We do not represent it as USP, BP, or EP grade.
How should 3,4-Difluorobenzylzinc bromide solution be handled safely?
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This compound is highly flammable and reacts violently with water, potentially forming explosive peroxides. Handle with extreme care in a well-ventilated area, away from ignition sources and moisture, using appropriate personal protective equipment.
How is this product packaged, shipped, and exported?
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This product is packaged according to UN 2924 8(3)/PGII regulations for flammable and corrosive substances. Tech Serve Solutions has extensive experience in exporting chemicals globally, adhering to all relevant international shipping regulations.
How can I request a sample or quote for 3,4-Difluorobenzylzinc bromide solution?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team directly via our website or by calling our customer service line.
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