(1S,2S)-trans-N-Boc-2-aminocyclohexanol
(1S,2S)-trans-N-Boc-2-aminocyclohexanol (CAS: 145166-06-9) is a chiral building block with the molecular formula C11H21NO3 and a molecular weight of 215.29 g/mol. This protected amino alcohol is valuable in asymmetric synthesis for constructing complex organic molecules. It serves as a key intermediate in various chemical synthesis pathways, particularly where stereochemical control is essential.
- Synonyms
- C11H21NO3

Asymmetric Synthesis
Utilised as a chiral auxiliary or building block in stereoselective reactions to create enantiomerically enriched compounds. Its defined stereochemistry allows for precise control over the formation of new chiral centres.
Pharmaceutical Intermediate
Serves as a precursor in the synthesis of active pharmaceutical ingredients (APIs) where specific chirality is required for biological activity. Enables the construction of complex drug molecules with defined stereochemistry.
Organic Synthesis
Employed in general organic synthesis as a versatile synthon for introducing chiral amine and alcohol functionalities into target molecules. Useful in multi-step syntheses requiring protected amino alcohols.
| Molecular weight | 215.29 |
|---|---|
| Empirical formula | C11H21NO3 |
| Assay | 95% |
| Optical purity | enantiomeric excess: ≥96.0% (GC) |


Hazard statements
- H302Harmful if swallowed
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-50 |
| Safety statements (S) | 61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S,2S)-trans-N-Boc-2-aminocyclohexanol used for?
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(1S,2S)-trans-N-Boc-2-aminocyclohexanol is primarily used as a chiral building block in asymmetric synthesis and for the preparation of pharmaceutical intermediates and other complex organic molecules where stereochemical control is crucial.
What are the CAS number and formula for this chemical?
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The CAS number for (1S,2S)-trans-N-Boc-2-aminocyclohexanol is 145166-06-9, and its empirical formula is C11H21NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1S,2S)-trans-N-Boc-2-aminocyclohexanol with an assay of 95% and an enantiomeric excess of ≥96.0% (GC). This product is supplied for research and development purposes and is not represented as USP, EP, or BP grade.
What are the main hazards associated with (1S,2S)-trans-N-Boc-2-aminocyclohexanol?
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This compound is classified with GHS07 and GHS09 symbols, indicating it is harmful if swallowed (H302) and very toxic to aquatic life (H400). Appropriate personal protective equipment, including a dust mask, eyeshields, faceshields, and gloves, should be used during handling.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions packages chemicals according to industry best practices to ensure safe transit. For export, all shipments comply with relevant international regulations, including UN 3077 9 / PGIII classification for this substance.
How can I request a sample or a quote?
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To request a sample or obtain a quote for (1S,2S)-trans-N-Boc-2-aminocyclohexanol, please visit the product page on our website or contact our sales department directly with your specific requirements.
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