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3,4-Difluorobenzoyl chloride

CAS 76903-88-3F2C6H3COClChemical Synthesis

3,4-Difluorobenzoyl chloride (CAS: 76903-88-3) is a fluorinated organic building block with the linear formula F2C6H3COCl and a molecular weight of 176.55 g/mol. This acid halide is primarily utilised in chemical synthesis, serving as a valuable intermediate for introducing the 3,4-difluorobenzoyl moiety into various organic molecules. Its reactive nature makes it suitable for diverse synthetic applications where precise fluorination is required.

Synonyms
F2C6H3COCl
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3,4-Difluorobenzoyl chloride (F2C6H3COCl) — chemical structure, CAS 76903-88-3; Chemistry, fine chemical supplied by Tech Serve Solutions
Acid HalidesBuilding BlocksCarbonyl CompoundsChemical SynthesisFluorinated Building BlocksOrganic Building Blocks
01 /Applications

Organic Synthesis Intermediate

3,4-Difluorobenzoyl chloride is employed as a key intermediate in the synthesis of complex organic molecules. Its structure allows for the introduction of a difluorinated aromatic ring, which is often desired in pharmaceutical and agrochemical research.

Research and Development

Utilised in R&D settings to explore new chemical pathways and create novel compounds. The presence of fluorine atoms can significantly alter the electronic and steric properties of molecules, making it an attractive building block for structure-activity relationship studies.

Specialty Chemical Manufacturing

Serves as a precursor in the production of specialty chemicals, including advanced materials and fine chemicals. Its reactivity as an acyl chloride enables versatile derivatisation.

02 /Properties
Molecular weight176.55
Linear formulaF2C6H3COCl
Assay98%
Density1.403 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.5114(lit.)
Application3,4-Difluorobenzoyl chloride may be used in chemical synthesis studies.
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point78 °C / 172.4 °F
Transport (UN / ADR)UN 3265 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
76903-88-3
MDL number
MFCD00009930
PubChem substance
24857450
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3,4-Difluorobenzoyl chloride used for?

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3,4-Difluorobenzoyl chloride is used as an intermediate in chemical synthesis, particularly for introducing the 3,4-difluorobenzoyl group into organic molecules during research and development.

What is the CAS number and formula for 3,4-Difluorobenzoyl chloride?

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The CAS number is 76903-88-3, and the linear formula is F2C6H3COCl.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 3,4-Difluorobenzoyl chloride with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How is 3,4-Difluorobenzoyl chloride handled and shipped?

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3,4-Difluorobenzoyl chloride is classified as corrosive (H314) and requires careful handling. It is shipped according to UN 3265, 8 / PGII regulations. Appropriate personal protective equipment, including gloves, goggles, and face shields, must be used. It is exported globally by Tech Serve Solutions.

How can I request a sample or quote for 3,4-Difluorobenzoyl chloride?

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To request a sample or a quotation, please contact our sales department via the website or by telephone. Our team will be pleased to assist you with your inquiry.

What are the primary hazards associated with 3,4-Difluorobenzoyl chloride?

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3,4-Difluorobenzoyl chloride causes severe skin burns and eye damage (H314). It is a corrosive substance that requires stringent safety precautions during handling and storage.

Need 3,4-Difluorobenzoyl chloride in a specific grade or volume?