3,4-Difluorobenzoic acid
3,4-Difluorobenzoic acid (CAS 455-86-7), with the linear formula F₂C₆H₃CO₂H and a molecular weight of 158.10 g/mol, is a valuable fluorinated organic building block. This carboxylic acid derivative is characterised by the presence of two fluorine atoms on the benzene ring, influencing its reactivity. It serves as an important intermediate in the synthesis of various organic compounds, particularly in the fields of medicinal chemistry and materials science, where fluorinated motifs are highly sought after.
- Synonyms
- F2C6H3CO2H
Pharmaceutical Intermediate
3,4-Difluorobenzoic acid is utilised as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Its difluorinated phenyl moiety can be incorporated into drug candidates to modulate properties such as metabolic stability and lipophilicity.
Agrochemical Synthesis
This compound finds application in the development of novel agrochemicals, including pesticides and herbicides. The introduction of fluorine atoms can enhance the efficacy and environmental profile of crop protection agents.
Materials Science
As a fluorinated aromatic compound, 3,4-Difluorobenzoic acid can be employed in the synthesis of advanced materials. These may include liquid crystals, polymers, and organic electronic components where specific electronic or physical properties are desired.
Research and Development
It is widely used in academic and industrial research laboratories as a versatile reagent for creating complex organic molecules and exploring new chemical pathways. Its specific substitution pattern makes it a useful synthon.
| Molecular weight | 158.10 |
|---|---|
| Linear formula | F2C6H3CO2H |
| Assay | 98% |
| Melting point | 120-122 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Difluorobenzoic acid primarily used for?
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3,4-Difluorobenzoic acid is primarily used as a building block and intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. It is also a common reagent in organic chemistry research and development.
What is the CAS number and formula for 3,4-Difluorobenzoic acid?
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The CAS number for 3,4-Difluorobenzoic acid is 455-86-7, and its linear formula is F₂C₆H₃CO₂H.
What grade and purity does Tech Serve Solutions supply for 3,4-Difluorobenzoic acid?
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Tech Serve Solutions supplies 3,4-Difluorobenzoic acid with a minimum assay of 98%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3,4-Difluorobenzoic acid be handled safely?
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3,4-Difluorobenzoic acid is harmful if swallowed and causes skin and eye irritation, and may cause respiratory irritation. When handling, wear a dust mask type N95 (US), use eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. In case of contact, rinse immediately with plenty of water.
Is 3,4-Difluorobenzoic acid available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3,4-Difluorobenzoic acid. We cater to international research and industrial needs.
How can I request a quote or sample for 3,4-Difluorobenzoic acid?
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To request a quote or sample for 3,4-Difluorobenzoic acid, please use the contact form on our website or reach out to our sales department directly. Specify the quantity and your delivery location.
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