3,4-Difluorobenzenesulfonamide
3,4-Difluorobenzenesulfonamide (CAS: 108966-71-8) is a fluorinated organic building block with the linear formula F2C6H3SO2NH2 and a molecular weight of 193.17 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly within the pharmaceutical and agrochemical sectors. Its unique difluorinated aromatic structure makes it a key component in the development of novel molecules requiring specific electronic and steric properties, contributing to advanced chemical research and development.
- Synonyms
- F2C6H3SO2NH2

Pharmaceutical Intermediate
3,4-Difluorobenzenesulfonamide is utilised in the synthesis of active pharmaceutical ingredients (APIs). Its fluorinated structure can impart desirable pharmacokinetic properties to drug candidates, such as increased metabolic stability and enhanced binding affinity.
Agrochemical Development
This compound finds application in the creation of novel agrochemicals, including herbicides, fungicides, and insecticides. The presence of fluorine atoms can influence the biological activity and environmental profile of these agricultural products.
Materials Science Research
As an organic fluorinated building block, it can be incorporated into advanced materials. Its unique electronic properties may be exploited in the design of specialised polymers or electronic materials.
Organic Synthesis
3,4-Difluorobenzenesulfonamide acts as a versatile reagent in complex organic synthesis pathways. It is suitable for reactions requiring a difluorinated aromatic scaffold for further functionalisation.
| Molecular weight | 193.17 |
|---|---|
| Linear formula | F2C6H3SO2NH2 |
| Assay | 97% |
| Melting point | 89-93 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Difluorobenzenesulfonamide used for?
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3,4-Difluorobenzenesulfonamide is primarily used as a building block in organic synthesis, particularly for creating intermediates in the pharmaceutical and agrochemical industries, and in materials science research.
What is the CAS number and molecular formula for 3,4-Difluorobenzenesulfonamide?
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The CAS number is 108966-71-8 and the linear molecular formula is F2C6H3SO2NH2.
What grade and purity does Tech Serve Solutions supply for 3,4-Difluorobenzenesulfonamide?
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Tech Serve Solutions supplies 3,4-Difluorobenzenesulfonamide with an assay of 97%. This is a research or technical grade material, and we do not represent it as USP, BP, or EP grade.
What are the safety and handling recommendations for 3,4-Difluorobenzenesulfonamide?
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Users should wear eyeshields and gloves. Respiratory protection with a type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK Germany 3, indicating a high hazard to water.
Can 3,4-Difluorobenzenesulfonamide be exported globally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3,4-Difluorobenzenesulfonamide, adhering to all necessary export regulations.
How can I request a quote or sample of 3,4-Difluorobenzenesulfonamide?
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To request a quote or sample, please contact our sales department through the website or by calling us. Our team will be pleased to assist you.
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