3,4-Difluoroaniline
3,4-Difluoroaniline (CAS: 3863-11-4) is a fluorinated organic building block with the molecular formula F₂C₆H₃NH₂ and a molecular weight of 129.11 g/mol. This aromatic amine is characterised by the presence of two fluorine atoms on the benzene ring. It serves as a valuable intermediate in the synthesis of various organic compounds, particularly in the development of novel materials and active pharmaceutical ingredients. Its specific substitution pattern makes it a useful synthon for introducing difluorophenyl moieties.
- Synonyms
- F2C6H3NH2
Synthesis of Fluoro-organic Compounds
3,4-Difluoroaniline is a key precursor in the synthesis of complex fluorinated organic molecules. Its reactive amine group allows for versatile functionalization, enabling its incorporation into diverse chemical structures.
Pharmaceutical Intermediate
The compound is utilised as a building block in the multi-step synthesis of active pharmaceutical ingredients (APIs). The difluorophenyl group can influence the pharmacokinetic and pharmacodynamic properties of drug candidates.
Material Science
It can be employed in the creation of specialized polymers and advanced materials where the incorporation of fluorine imparts unique properties such as thermal stability and altered electronic characteristics.
Agrochemical Development
3,4-Difluoroaniline may serve as an intermediate in the development of new agrochemicals, leveraging the influence of fluorine substitution on biological activity.
| Molecular weight | 129.11 |
|---|---|
| Linear formula | F2C6H3NH2 |
| Assay | 99% |
| Boiling point | 77 °C/7 mmHg(lit.) |
| Density | 1.302 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.513(lit.) |
| Application | 3,4-Difluoroaniline was used in the synthesis of (3,4-disfluoro)phenylquione1. |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 85 °C / 185 °F |
| Transport (UN / ADR) | UN 2941 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Difluoroaniline used for?
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3,4-Difluoroaniline (CAS: 3863-11-4) is primarily used as a building block and intermediate in organic synthesis, particularly for creating fluorinated organic compounds, pharmaceuticals, and potentially in material science and agrochemical research.
What are the CAS number and chemical formula for 3,4-Difluoroaniline?
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The CAS number for 3,4-Difluoroaniline is 3863-11-4, and its linear formula is F₂C₆H₃NH₂.
What grade and purity does Tech Serve Solutions supply for 3,4-Difluoroaniline?
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Tech Serve Solutions supplies 3,4-Difluoroaniline with a purity of 99% (assay). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product data.
How should 3,4-Difluoroaniline be handled safely?
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3,4-Difluoroaniline is classified with Warning signal word and hazards including H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Always use appropriate personal protective equipment, such as gloves, safety glasses with side-shields, and ensure adequate ventilation. Refer to the Safety Data Sheet (SDS) for comprehensive handling and emergency procedures.
Is 3,4-Difluoroaniline a controlled substance?
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The provided data does not indicate that 3,4-Difluoroaniline (CAS: 3863-11-4) is a controlled substance.
How is 3,4-Difluoroaniline packed, shipped, and exported?
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3,4-Difluoroaniline is packed according to industry standards for chemical safety and integrity. As a global supplier, Tech Serve Solutions handles all aspects of shipping and export documentation to ensure compliance with international regulations.
How can I request a quote or sample of 3,4-Difluoroaniline?
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To request a quote or sample of 3,4-Difluoroaniline, please use the contact form on our website or contact our sales department directly with your requirements.
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