4-Fluoro-3-(trifluoromethyl)phenylacetic acid
4-Fluoro-3-(trifluoromethyl)phenylacetic acid (CAS: 220227-47-4) is a fluorinated organic building block with the molecular formula FC6H3(CF3)CH2CO2H and a molecular weight of 222.14 g/mol. This carboxylic acid derivative serves as a valuable intermediate in organic synthesis, particularly in the development of new pharmaceutical compounds and agrochemicals. Its unique structure, featuring both fluorine and trifluoromethyl substituents on the phenyl ring, allows for precise modification in advanced chemical research and development processes.
Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs), contributing fluorine and trifluoromethyl moieties for targeted drug design and enhanced pharmacokinetic properties.
Agrochemical Development
Serves as a key building block for novel pesticides, herbicides, and fungicides, where fluorination can improve efficacy and environmental persistence.
Materials Science Research
Investigated for incorporation into advanced materials due to the unique electronic and physical properties conferred by its fluorinated structure.
Chemical Synthesis
A versatile reagent employed in various organic transformations, facilitating the introduction of a specific fluorinated phenylacetic acid scaffold into complex molecules.
| Molecular weight | 222.14 |
|---|---|
| Linear formula | FC6H3(CF3)CH2CO2H |
| Assay | 97% |
| Melting point | 51-55 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-3-(trifluoromethyl)phenylacetic acid used for?
+
4-Fluoro-3-(trifluoromethyl)phenylacetic acid is primarily used as a building block in organic synthesis, particularly for the development of pharmaceutical intermediates and agrochemicals.
What is the CAS number and formula for this compound?
+
The CAS number is 220227-47-4, and the molecular formula is FC6H3(CF3)CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this product with an assay of 97%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product data.
How should 4-Fluoro-3-(trifluoromethyl)phenylacetic acid be handled?
+
This compound is a Warning substance classified with hazards H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). It requires the use of a dust mask type N95 (US), Eyeshields, and Gloves for safe handling. Please refer to the safety data sheet for full details.
Is 4-Fluoro-3-(trifluoromethyl)phenylacetic acid a controlled substance?
+
The provided data does not indicate that 4-Fluoro-3-(trifluoromethyl)phenylacetic acid is a controlled substance.
How is this chemical exported and what are the packing options?
+
Tech Serve Solutions is a global supplier and exporter of fine chemicals. Specific packing and shipping details are available upon request, tailored to meet international regulations and customer requirements.
How can I request a quote or sample?
+
To request a quote or sample of 4-Fluoro-3-(trifluoromethyl)phenylacetic acid, please contact our sales team through the website or by phone, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis