4-Fluoro-3-(trifluoromethyl)benzoyl chloride
4-Fluoro-3-(trifluoromethyl)benzoyl chloride (CAS 67515-56-4), with the linear formula C8H3ClF4O, is a reactive acid halide. This fluorinated organic compound serves as a valuable intermediate and building block in organic synthesis, particularly for introducing the 4-fluoro-3-(trifluoromethyl)benzoyl moiety into target molecules. Its primary applications lie in the research and development of novel pharmaceuticals and agrochemicals.
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) where the trifluoromethyl and fluorine substituents are desired for modulating drug properties such as lipophilicity and metabolic stability.
Agrochemical Synthesis
Serves as a key building block for developing new pesticides, herbicides, and fungicides, leveraging the unique electronic and steric effects of the fluorinated benzoyl group.
Organic Synthesis Reagent
A versatile reagent for acylation reactions, enabling the formation of esters, amides, and ketones in complex organic molecule construction.
Materials Science
Investigated for incorporation into advanced materials and polymers where its specific chemical structure may impart unique thermal or electronic properties.
| Molecular weight | 226.56 |
|---|---|
| Linear formula | FC6H3(CF3)COCl |
| Assay | 98% |
| Boiling point | 170 °C(lit.) |
| Density | 1.493 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.469(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 77 °C / 170.6 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-3-(trifluoromethyl)benzoyl chloride used for?
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4-Fluoro-3-(trifluoromethyl)benzoyl chloride is primarily used as an intermediate and building block in the synthesis of pharmaceuticals and agrochemicals, and in general organic synthesis for acylation reactions.
What is the CAS number and formula for 4-Fluoro-3-(trifluoromethyl)benzoyl chloride?
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The CAS number is 67515-56-4 and the linear formula is C8H3ClF4O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-3-(trifluoromethyl)benzoyl chloride with a purity of 98%. This is a technical/research grade, and TSS does not represent it as USP/BP/EP.
How should 4-Fluoro-3-(trifluoromethyl)benzoyl chloride be handled?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment including faceshields, full-face respirators, gloves, and goggles must be used. Handle in a well-ventilated area or fume hood.
Is 4-Fluoro-3-(trifluoromethyl)benzoyl chloride packed and shipped internationally?
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Yes, Tech Serve Solutions exports this chemical globally. It is shipped according to international regulations for hazardous materials (UN 3265, Class 8, PG II).
How can I request a sample or quote for 4-Fluoro-3-(trifluoromethyl)benzoyl chloride?
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Please contact our sales team via the website or direct inquiry to request a sample or obtain a quotation for 4-Fluoro-3-(trifluoromethyl)benzoyl chloride.
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