4-Fluoro-3-hydroxybenzoic acid
4-Fluoro-3-hydroxybenzoic acid (CAS 51446-31-2) is a fluorinated organic compound with the molecular formula FC6H3(OH)CO2H and a molecular weight of 156.11 g/mol. This aromatic carboxylic acid serves as a valuable building block in organic synthesis. It is primarily utilised in research and development for the creation of novel compounds, including potential pharmaceutical intermediates and materials science applications, owing to its specific structural features.

Organic Synthesis Intermediate
4-Fluoro-3-hydroxybenzoic acid is employed as a versatile intermediate in complex organic syntheses. Its functional groups (carboxyl, hydroxyl, and fluorine) allow for diverse chemical transformations, facilitating the construction of intricate molecular architectures.
Pharmaceutical Research
This compound finds application in the research and development of new drug candidates. The presence of fluorine can modulate a molecule's pharmacokinetic properties, making it an attractive component in medicinal chemistry programmes.
Materials Science
As a building block, 4-Fluoro-3-hydroxybenzoic acid can be incorporated into polymers or other advanced materials. Its structure may impart desirable thermal, electronic, or optical properties to the resulting materials.
| Molecular weight | 156.11 |
|---|---|
| Linear formula | FC6H3(OH)CO2H |
| Assay | 97% |
| Melting point | 214-218 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-3-hydroxybenzoic acid used for?
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4-Fluoro-3-hydroxybenzoic acid is primarily used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research and potentially in materials science.
What are the CAS number and chemical formula for 4-Fluoro-3-hydroxybenzoic acid?
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The CAS number is 51446-31-2 and the chemical formula is FC6H3(OH)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-3-hydroxybenzoic acid with an assay of 97%. We do not represent this product as USP, BP, or EP grade; it is supplied for research and laboratory use.
How should 4-Fluoro-3-hydroxybenzoic acid be handled safely?
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4-Fluoro-3-hydroxybenzoic acid is a Warning substance that can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation.
Does Tech Serve Solutions export 4-Fluoro-3-hydroxybenzoic acid?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Fluoro-3-hydroxybenzoic acid.
How can I request a sample or quote for 4-Fluoro-3-hydroxybenzoic acid?
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To request a sample or quote, please contact our sales team through the website or by phone, providing the product name and CAS number (51446-31-2).
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