3,4-Difluorobenzaldehyde
3,4-Difluorobenzaldehyde (CAS 34036-07-2) is a fluorinated aromatic aldehyde with the molecular formula F₂C₆H₃CHO and a molecular weight of 142.10 g/mol. This compound serves as a valuable building block in organic synthesis. It is primarily utilised in the creation of more complex molecules, including derivatives for chemical research and pharmaceutical intermediate development, owing to its reactive aldehyde group and the presence of fluorine atoms on the aromatic ring.
- Synonyms
- F2C6H3CHO3,4-Difluorobenzene-1-carbaldehyde
Synthesis of Organic Intermediates
3,4-Difluorobenzaldehyde functions as a key starting material for synthesising diverse organic compounds. Its structural features, particularly the difluorinated phenyl ring and the aldehyde functionality, make it adaptable for various synthetic transformations.
Pharmaceutical Research
This compound is employed in the development of novel pharmaceutical candidates. For instance, it has been used in the synthesis of specific derivatives of betulinic acid, contributing to research in medicinal chemistry.
Fluorinated Building Block
As a fluorinated aromatic building block, 3,4-Difluorobenzaldehyde is instrumental in introducing fluorine atoms into target molecules. This is important in medicinal chemistry and materials science where fluorination can significantly alter compound properties.
| Molecular weight | 142.10 |
|---|---|
| Linear formula | F2C6H3CHO |
| Assay | 97% |
| Density | 1.288 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5(lit.) |
| Application | 3,4-Difluorobenzaldehyde was used in the synthesis of 3-benzylidene 20,29-dihydrobetulinic acid derivatives1. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 66 °C / 150.8 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Difluorobenzaldehyde used for?
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3,4-Difluorobenzaldehyde is primarily used as a building block in organic synthesis, particularly for creating fluorinated organic compounds and pharmaceutical intermediates. It was notably used in the synthesis of 3-benzylidene 20,29-dihydrobetulinic acid derivatives.
What are the CAS number and molecular formula for 3,4-Difluorobenzaldehyde?
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The CAS number for 3,4-Difluorobenzaldehyde is 34036-07-2, and its linear molecular formula is F₂C₆H₃CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-Difluorobenzaldehyde with a minimum assay of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should 3,4-Difluorobenzaldehyde be handled safely?
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3,4-Difluorobenzaldehyde is classified with Warning signal word and hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator (e.g., type ABEK EN14387 filter), should be used. Ensure adequate ventilation, and follow precautionary statements P261 (Avoid breathing dust/fume/gas/mist/vapours/spray) and P305 + P351 + P338 (IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing).
How is 3,4-Difluorobenzaldehyde shipped and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. 3,4-Difluorobenzaldehyde is available for export worldwide, adhering to all necessary shipping regulations for chemical substances.
How can I request a quote or sample for 3,4-Difluorobenzaldehyde?
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To request a quote or a sample of 3,4-Difluorobenzaldehyde, please contact the TSS sales team via our website or direct inquiry channels. Our team will promptly assist you with your requirements.
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