3,4-Difluorobenzenesulfonyl chloride
3,4-Difluorobenzenesulfonyl chloride (CAS: 145758-05-0) is a chemical intermediate with the molecular formula C6H3Cl F2O2S and a molecular weight of 212.60 g/mol. This compound serves as a valuable building block in organic synthesis, particularly for introducing the 3,4-difluorobenzenesulfonyl moiety into more complex molecules. Its reactivity makes it useful in the development of novel materials and active pharmaceutical ingredients.
- Synonyms
- F2C6H3SO2Cl
Organic Synthesis Intermediate
Used as a key building block in the synthesis of complex organic molecules. Its sulfonyl chloride functionality allows for facile reactions with nucleophiles, enabling the formation of sulfonamides, sulfonates, and other sulfur-containing derivatives.
Pharmaceutical Research
Incorporated into the design and synthesis of potential drug candidates. The presence of fluorine atoms can influence metabolic stability, lipophilicity, and binding affinity of pharmaceutical compounds.
Materials Science
Can be utilized in the development of novel polymers or functional materials. The difluorinated aromatic ring may impart unique electronic or physical properties to the resulting materials.
| Molecular weight | 212.60 |
|---|---|
| Linear formula | F2C6H3SO2Cl |
| Assay | 97% |
| Boiling point | 212 °C(lit.) |
| Density | 1.586 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.515(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Difluorobenzenesulfonyl chloride used for?
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3,4-Difluorobenzenesulfonyl chloride (CAS: 145758-05-0) is primarily used as an intermediate in organic synthesis for introducing the 3,4-difluorobenzenesulfonyl group into other molecules, finding applications in pharmaceutical research and materials science.
What are the CAS number and chemical formula?
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The CAS number for 3,4-Difluorobenzenesulfonyl chloride is 145758-05-0, and its linear chemical formula is F2C6H3SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-Difluorobenzenesulfonyl chloride with an assay of 97%. This product is a research-grade chemical and is not intended for USP, BP, EP, or other pharmacopoeia applications unless explicitly stated.
How should 3,4-Difluorobenzenesulfonyl chloride be handled?
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3,4-Difluorobenzenesulfonyl chloride is a corrosive substance (H314) and requires stringent safety precautions. Handle with appropriate personal protective equipment, including full-face respirators, chemical-resistant gloves, and goggles. Ensure adequate ventilation and immediate access to an eyewash station and safety shower.
How is this chemical packed and shipped?
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This product is packed in accordance with international regulations for hazardous materials and is exported globally by Tech Serve Solutions. Shipments are classified under UN 3265, 8 / PGII, indicating it is a corrosive liquid, acidic, organic, n.o.s.
How can I request a quote or sample?
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To request a quote or a sample of 3,4-Difluorobenzenesulfonyl chloride, please use the 'Request a Quote' or 'Request a Sample' button on our product page, or contact our sales team directly with your requirements.
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