2′-Dicyclohexylphosphino-2,4,6-trimethoxybiphenyl

CAS 1000171-05-0C27H37O3PCatalysis & Inorganic

2′-Dicyclohexylphosphino-2,4,6-trimethoxybiphenyl (CAS: 1000171-05-0) is a highly effective phosphine ligand with the molecular formula C27H37O3P and a molecular weight of 440.55. This Buchwald ligand is specifically utilised as a catalyst in crucial organic synthesis reactions, particularly the Suzuki-Miyaura cross-coupling of phenyl tosylates with potassium (phenyl)trifluoroborates. Its efficacy in facilitating these carbon-carbon bond formations makes it an invaluable tool for synthetic chemists.

IUPAC: Dicyclohexyl(2′,4′,6′-trimethoxy[1,1′-biphenyl]-2-yl)-phosphine
Synonyms: 1000171-05-0C27H37O3PDicyclohexyl(2′,4′,6′-trimethoxy[1,1′-biphenyl]-2-yl)-phosphine

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2′-Dicyclohexylphosphino-2,4,6-trimethoxybiphenyl (C27H37O3P) — chemical structure, CAS 1000171-05-0; Chemistry, fine chemical supplied by Tech Serve Solutions

Buchwald LigandsChemical SynthesisCross-CouplingPhosphine Compounds More...

01 /Applications

Suzuki-Miyaura Cross-Coupling Catalyst

This compound functions as a key phosphine ligand in the Suzuki-Miyaura cross-coupling reaction. It facilitates the formation of carbon-carbon bonds by catalysing the reaction between phenyl tosylates and potassium (phenyl)trifluoroborates.

Advanced Organic Synthesis

As a specialised Buchwald ligand, it is employed in complex organic synthesis pathways. Its unique structure supports efficient catalytic cycles, enabling the construction of sophisticated molecular architectures.

Catalysis Research

Researchers utilise this compound to explore and optimise catalytic processes. Its application in cross-coupling reactions makes it a valuable reagent for developing new synthetic methodologies in catalysis and inorganic chemistry.

02 /Properties

Molecular weight	440.55
Empirical formula	C27H37O3P
Assay	97%
Application	Catalyst for Suzuki-Miyaura cross-coupling of Ph tosylates with potassium (phenyl)trifuoroborates1
Melting point	148-158 °C

03 /Safety & handling

Hazard statements

H413May cause long-lasting harmful effects to aquatic life

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	2

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1000171-05-0

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2′-Dicyclohexylphosphino-2,4,6-trimethoxybiphenyl used for?

This compound is primarily used as a catalyst, specifically a Buchwald ligand, for Suzuki-Miyaura cross-coupling reactions, particularly involving phenyl tosylates and potassium (phenyl)trifluoroborates.

What is the CAS number and molecular formula for 2′-Dicyclohexylphosphino-2,4,6-trimethoxybiphenyl?

The CAS number is 1000171-05-0, and the molecular formula is C27H37O3P.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety precautions when handling this chemical?

Handle with care, wearing eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound may cause long-lasting harmful effects to aquatic life (H413).

How is 2′-Dicyclohexylphosphino-2,4,6-trimethoxybiphenyl packed and shipped?

Tech Serve Solutions expertly packs and exports fine chemicals globally, adhering to stringent international shipping regulations for chemical products.