(RP,R′P)-1,1′-Bis[(S)-α-(dimethylamino)benzyl]-2,2′-bis(diphenylphosphino)ferrocene
(RP,R′P)-1,1′-Bis[(S)-α-(dimethylamino)benzyl]-2,2′-bis(diphenylphosphino)ferrocene (CAS 223725-09-5) is a chiral ferrocene-based diphosphine ligand with a molecular weight of 820.76 g/mol. This compound is primarily recognised for its utility as a privileged ligand in asymmetric synthesis, particularly in metal-catalyzed enantioselective reactions. Its unique structural features enable high stereoselectivity in various chemical transformations, making it a valuable tool for the synthesis of chiral molecules.
- IUPAC
- (2S,2′S)-1,1′-Bis[(S)-(dimethylamino)phenylmethyl]-2,2′-bis(diphenylphosphino)ferrocene (acc to CAS),Mandyphos SL-M001-2
- Synonyms
- 2′-bis(diphenylphosphino)ferroceneC52H50FeN2P2Mandyphos SL-M001-2(2S,2′S)-1,1′-Bis[(S)-(dimethylamino)phenylmethyl]-2,2′-bis(diphenylphosphino)ferrocene
![(RP,R′P)-1,1′-Bis[(S)-α-(dimethylamino)benzyl]-2,2′-bis(diphenylphosphino)ferrocene (C52H50FeN2P2) — chemical structure, CAS 223725-09-5; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F223725-09-5.png&w=3840&q=75)
Asymmetric Catalysis
Utilized as a chiral ligand in transition metal catalysis to promote enantioselective transformations. It is particularly effective in reactions requiring high stereocontrol, enabling the synthesis of enantiomerically pure compounds.
Chiral Ligand Development
Serves as a key component in the development of novel chiral catalytic systems. Its rigid ferrocene backbone and coordinating phosphine groups facilitate precise control over the stereochemical outcome of catalytic reactions.
Pharmaceutical Intermediate Synthesis
Employed in the synthesis of complex chiral molecules that are often intermediates in the production of pharmaceuticals. The high enantioselectivity offered by this ligand is crucial for producing active pharmaceutical ingredients (APIs) with desired stereochemistry.
| Molecular weight | 820.76 |
|---|---|
| Empirical formula | C52H50FeN2P2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (RP,R′P)-1,1′-Bis[(S)-α-(dimethylamino)benzyl]-2,2′-bis(diphenylphosphino)ferrocene used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis and catalysis, enabling the enantioselective production of chiral molecules, often serving as intermediates in pharmaceutical synthesis.
What is the CAS number and formula for this compound?
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The CAS number is 223725-09-5 and the empirical formula is C52H50FeN2P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97% and an optical purity of ee: ≥99%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
What are the safety considerations for handling this chemical?
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This compound has a WGK Germany rating of 3, indicating it is hazardous. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used during handling to avoid exposure.
How is this chemical packed and shipped by TSS?
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Tech Serve Solutions packs and ships fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all necessary regulations for safe transport.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales department through the provided channels on our website.
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