2′-(Di-tert-butylphosphino)acetophenone ethylene ketal
2′-(Di-tert-butylphosphino)acetophenone ethylene ketal (CAS: 1202864-99-0) is an organophosphorus compound with the formula C18H29O2P and a molecular weight of 308.40 g/mol. This phosphine ligand, with its protected phosphine functionality, is primarily utilised in chemical synthesis as a building block or ligand in catalytic applications. Its structure makes it valuable for introducing specific phosphine moieties in complex molecule construction.
- IUPAC
- 2-(2-Di-tert-butylphosphinophenyl)-2-methyl-1,3-dioxolane,Bis(1,1-dimethylethyl)[2-(2-methyl-1,3-dioxolan-2-yl)phenyl]-phosphine
- Synonyms
- 2-(2-Di-tert-butylphosphinophenyl)-2-methyl-1,3-dioxolaneBis(1,1-dimethylethyl)[2-(2-methyl-1,3-dioxolan-2-yl)phenyl]-phosphine

Catalysis and Ligand Design
This compound serves as a valuable phosphine ligand in various catalytic transformations. The di-tert-butylphosphino group offers steric bulk, influencing catalyst activity and selectivity. The ethylene ketal provides a protecting group that can be selectively removed under specific conditions, allowing for further functionalization or tuning of the ligand.
Organic Synthesis Intermediate
As a functionalized phosphine, it acts as an intermediate in the synthesis of more complex organophosphorus compounds. Its unique structure can be incorporated into larger molecules, contributing specific electronic or steric properties to the final product, particularly in the development of novel materials or pharmaceuticals.
Research and Development
This chemical is employed in academic and industrial research settings for exploring new synthetic methodologies and catalytic systems. Researchers utilise its specific structure to investigate reaction mechanisms and develop innovative chemical processes.
| Molecular weight | 308.40 |
|---|---|
| Empirical formula | C18H29O2P |
| Assay | 97% |
| Melting point | 85-89 °C |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-(Di-tert-butylphosphino)acetophenone ethylene ketal used for?
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2′-(Di-tert-butylphosphino)acetophenone ethylene ketal is primarily used as a phosphine ligand in catalysis and as an intermediate in organic synthesis, particularly in research and development settings.
What are the CAS number and formula for this compound?
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The CAS number is 1202864-99-0 and the empirical formula is C18H29O2P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2′-(Di-tert-butylphosphino)acetophenone ethylene ketal be handled?
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This compound is harmful to aquatic life with long-lasting effects (H413). When handling, it is essential to wear eyeshields and gloves, and use an appropriate respirator filter (type N95 or P1). Ensure adequate ventilation.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions professionally packs, handles, and exports fine chemicals globally, adhering to all necessary regulations for safe and compliant transport.
How can I request a sample or quote?
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To request a sample or a quote for 2′-(Di-tert-butylphosphino)acetophenone ethylene ketal, please contact our sales team through the website or by phone.
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