α-(Boc-amino)phenethylamine
α-(Boc-amino)phenethylamine (CAS: 142910-85-8, C13H20N2O2) is a protected amine building block with a molecular weight of 236.31. This compound is primarily utilised in organic synthesis as a reactant for preparing complex molecules. Its structure features a Boc-protected amino group and a phenethylamine backbone, making it valuable for introducing specific functionalities in multi-step synthetic pathways, particularly in the development of novel pharmaceutical intermediates and research chemicals.
- IUPAC
- (2-Amino-1-phenyl-ethyl)carbamic acid tert-butyl ester,1,1-Dimethylethyl (2-amino-1-phenylethyl)carbamate,2-(Boc-amino)-2-phenylethanamine,tert-Butyl-(2-amino-1-phenylethyl)carbamate
- Synonyms
- (2-Amino-1-phenyl-ethyl)carbamic acid tert-butyl ester1,1-Dimethylethyl (2-amino-1-phenylethyl)carbamate2-(Boc-amino)-2-phenylethanaminetert-Butyl-(2-amino-1-phenylethyl)carbamate
Synthesis of γ-Lactams
This compound serves as a key reactant in the preparation of gamma-lactams from carboxylic acids and amines. It is specifically employed in Ugi/De-BOC/Cyclize (UDC) strategies when isonitriles are involved, facilitating efficient ring formation.
Organic Synthesis Building Block
As a protected amine, α-(Boc-amino)phenethylamine is a versatile building block in general organic synthesis. It allows for selective reactions by protecting the amine functionality during transformations elsewhere in the molecule.
Pharmaceutical Intermediate Development
The compound's structure is relevant for the synthesis of potential pharmaceutical intermediates. Its incorporation into larger molecules can lead to novel drug candidates or analogues in medicinal chemistry research.
| Molecular weight | 236.31 |
|---|---|
| Empirical formula | C13H20N2O2 |
| Application | Reactant for:• Preparation of γ-lactams from carboxylic acids and amines via UDC (Ugi/De-BOC/Cyclize) strategy using isonitriles1 |
| Melting point | 85-90 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is α-(Boc-amino)phenethylamine used for?
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α-(Boc-amino)phenethylamine is used as a reactant in the preparation of γ-lactams via Ugi/De-BOC/Cyclize strategies and as a versatile building block in general organic synthesis, particularly for pharmaceutical intermediate development.
What are the CAS number and molecular formula of α-(Boc-amino)phenethylamine?
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The CAS number for α-(Boc-amino)phenethylamine is 142910-85-8, and its molecular formula is C13H20N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research or technical grade chemical. We do not represent it as USP, BP, EP, or for any other pharmacopoeia, food, or nutraceutical use.
How should α-(Boc-amino)phenethylamine be handled and stored?
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This compound is classified as Dangerous. It causes severe skin burns and eye damage (H315, H318) and may cause respiratory irritation (H335). Harmful if swallowed (H302). Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection if ventilation is inadequate. Store in a well-ventilated place. Keep container tightly closed.
Is α-(Boc-amino)phenethylamine a controlled substance?
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This compound is not listed as a controlled substance in the provided data.
How can I request a sample or quote for α-(Boc-amino)phenethylamine?
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To request a sample or quote, please contact our sales team via the website or direct email, providing the product name and CAS number (142910-85-8).
How is α-(Boc-amino)phenethylamine packed and exported?
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Tech Serve Solutions professionally packs and exports fine chemicals globally, adhering to all necessary regulations for safe and compliant transportation.
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