3,4-Difluoronitrobenzene
3,4-Difluoronitrobenzene (CAS: 369-34-6), with the molecular formula F₂C₆H₃NO₂ and a molecular weight of 159.09 g/mol, is a valuable organic building block. This fluorinated nitro compound is primarily utilised in chemical synthesis for the preparation of more complex molecules. Its structure, featuring two fluorine atoms and a nitro group on a benzene ring, makes it a useful intermediate in the development of pharmaceuticals and other fine chemicals.
- IUPAC
- 1,2-Difluoro-4-nitrobenzene
- Synonyms
- 1,2-Difluoro-4-nitrobenzeneF2C6H3NO2
Synthesis of Xanthones and Acridones
3,4-Difluoronitrobenzene serves as a key precursor in the synthetic pathways leading to xanthone and acridone derivatives. These heterocyclic compounds often form the core structures of various biologically active molecules and advanced materials.
Aryl Fluorinated Building Block
As a difluorinated nitroaromatic, this compound is an important building block in organic synthesis. It enables the introduction of a difluoronitrophenyl moiety into target molecules, facilitating the creation of novel fluorinated organic compounds for research and development.
Intermediate in Chemical Synthesis
The compound's reactivity allows for diverse chemical transformations, making it a versatile intermediate. Its applications span across academic research and industrial chemical synthesis, contributing to the development of new chemical entities.
| Molecular weight | 159.09 |
|---|---|
| Linear formula | F2C6H3NO2 |
| Assay | 99% |
| Boiling point | 76-80 °C/11 mmHg(lit.) |
| Density | 1.437 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.509(lit.) |
| Application | 3,4-Difluoronitrobenzene was used in the preparation of xanthones and acridones1. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 81 °C / 177.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Difluoronitrobenzene used for?
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3,4-Difluoronitrobenzene is used as a building block in chemical synthesis, notably in the preparation of xanthones and acridones. It is a key intermediate for introducing difluoronitrophenyl groups into organic molecules.
What is the CAS number and chemical formula for 3,4-Difluoronitrobenzene?
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The CAS number for 3,4-Difluoronitrobenzene is 369-34-6, and its linear formula is F₂C₆H₃NO₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-Difluoronitrobenzene with an assay of 99%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmaceutical grade.
How should 3,4-Difluoronitrobenzene be handled safely?
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3,4-Difluoronitrobenzene is a warning substance that can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). When handling, wear appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator. Ensure adequate ventilation in the work area.
How is 3,4-Difluoronitrobenzene packed and shipped?
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3,4-Difluoronitrobenzene is carefully packed in compliance with international regulations for chemical transport. Tech Serve Solutions exports this chemical globally to meet the needs of researchers and manufacturers worldwide.
How can I request a sample or quote for 3,4-Difluoronitrobenzene?
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To request a sample or a quote for 3,4-Difluoronitrobenzene, please contact our sales team through the website or by phone. Provide your contact details and the quantity required.
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