(S)-α-Allyl-proline hydrochloride
(S)-α-Allyl-proline hydrochloride (CAS: 129704-91-2; Formula: C8H13NO2 · HCl; MW: 191.66) is a specialised unnatural amino acid derivative. As a key building block, it is primarily utilised in chemical synthesis and peptide chemistry for the development of novel compounds and modified peptides. Its unique structural features make it valuable in chemical biology research and for creating complex molecular architectures.
- IUPAC
- α-Allyl-D-proline hydrochloride,(S)-2-Allyl-2-pyrrolidinecarboxylic acid hydrochloride
- Synonyms
- (S)-2-Allyl-2-pyrrolidinecarboxylic acid hydrochlorideα-Allyl-D-proline hydrochloride

Chemical Synthesis
Serves as a versatile chiral building block in organic synthesis, enabling the construction of complex molecular scaffolds with defined stereochemistry.
Peptide Chemistry
Incorporated into peptide sequences to introduce unique structural modifications and enhance biological activity or stability.
Chemical Biology
Utilised as a tool compound in probing biological pathways and developing novel therapeutic agents.
Unnatural Amino Acid Research
A valuable reagent for researchers exploring the structure-activity relationships of peptides and proteins containing non-canonical amino acids.
| Molecular weight | 191.66 |
|---|---|
| Empirical formula | C8H13NO2 · HCl |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-α-Allyl-proline hydrochloride used for?
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(S)-α-Allyl-proline hydrochloride is primarily used in chemical synthesis, peptide chemistry, chemical biology research, and as an unnatural amino acid derivative for creating novel compounds.
What are the CAS number and formula for (S)-α-Allyl-proline hydrochloride?
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The CAS number is 129704-91-2 and the empirical formula (Hill notation) is C8H13NO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-α-Allyl-proline hydrochloride with an assay of ≥98.0% (TLC). We do not represent this product as USP, BP, or EP grade.
What safety precautions should be taken when handling this chemical?
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Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound is classified under WGK 3 in Germany, indicating a high hazard.
How is this product shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and this product is available for international shipment.
How can I request a sample or quote for (S)-α-Allyl-proline hydrochloride?
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Please contact our sales team via the website or email to request a sample or a formal quotation for (S)-α-Allyl-proline hydrochloride.
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