Boc-α-(diphenylmethyl)-DL-Pro-OH
1-Boc-2-(diphenylmethyl)-2-pyrrolidinecarboxylic acid (CAS: 351002-64-7), with the molecular formula C23H27NO4 and a molecular weight of 381.46 g/mol, is a proline derivative. This unnatural amino acid derivative is essential in various chemical biology and synthesis applications, particularly within peptide chemistry. It serves as a valuable building block for creating complex peptides and peptidomimetics.
- IUPAC
- 1-Boc-2-(diphenylmethyl)-2-pyrrolidinecarboxylic acid,Boc-α-(benzhydryl)-DL-proline,Boc-α-(diphenylmethyl)-DL-proline
- Synonyms
- 1-Boc-2-(diphenylmethyl)-2-pyrrolidinecarboxylic acidBoc-α-(benzhydryl)-DL-prolineBoc-α-(diphenylmethyl)-DL-proline

Peptide Synthesis
Utilised as a protected unnatural amino acid, it enables the controlled incorporation of modified proline residues into peptide chains. This allows for the synthesis of peptides with altered structural, functional, or stability properties.
Chemical Biology Research
Serves as a key intermediate in the development of novel biologically active molecules and probes. Its unique structure aids in studying protein-ligand interactions and enzyme mechanisms.
Organic Synthesis
Acts as a chiral building block in the asymmetric synthesis of complex organic molecules beyond peptides. Its functional groups allow for diverse synthetic transformations.
| Molecular weight | 381.46 |
|---|---|
| Empirical formula | C23H27NO4 |
| Assay | ≥90% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-α-(diphenylmethyl)-DL-Pro-OH used for?
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Boc-α-(diphenylmethyl)-DL-Pro-OH is primarily used as a protected unnatural amino acid in peptide synthesis and as a building block in chemical biology and organic synthesis research.
What is the CAS number and formula for Boc-α-(diphenylmethyl)-DL-Pro-OH?
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The CAS number is 351002-64-7 and the empirical formula is C23H27NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥90% (HPLC). We do not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should Boc-α-(diphenylmethyl)-DL-Pro-OH be handled?
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When handling this compound, it is advised to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if respiratory protection is needed. The compound is classified under WGK-Germany 3.
Is Boc-α-(diphenylmethyl)-DL-Pro-OH available for export?
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Yes, as a specialist global supplier and exporter of fine chemicals, Tech Serve Solutions can export Boc-α-(diphenylmethyl)-DL-Pro-OH.
How can I request a sample or quote for Boc-α-(diphenylmethyl)-DL-Pro-OH?
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Please contact our sales team directly to request a sample or a detailed quotation for Boc-α-(diphenylmethyl)-DL-Pro-OH.
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