Boc-α-(4-bromobenzyl)-DL-Pro-OH
Boc-α-(4-bromobenzyl)-DL-Pro-OH (CAS: 336817-91-5) is a protected unnatural amino acid derivative, featuring a tert-butyloxycarbonyl (Boc) group and a 4-bromobenzyl substituent on the proline ring. With a molecular weight of 384.26 g/mol and empirical formula C17H22BrNO4, it is primarily utilised in chemical synthesis and peptide chemistry for the construction of modified peptides and complex organic molecules. Its structure makes it a valuable building block in research and development.
- IUPAC
- 1-Boc-2-(4-bromobenzyl)-2-pyrrolidinecarboxylic acid,Boc-α-(4-bromobenzyl)-DL-proline
- Synonyms
- 1-Boc-2-(4-bromobenzyl)-2-pyrrolidinecarboxylic acidBoc-α-(4-bromobenzyl)-DL-proline

Peptide Synthesis
Serves as a key building block in solid-phase or solution-phase peptide synthesis for incorporating unnatural amino acid residues. It allows for the creation of peptides with modified structures and potentially altered biological activities.
Medicinal Chemistry
Utilised in the design and synthesis of novel drug candidates. The bromobenzyl and proline moieties can be incorporated into molecular scaffolds to explore structure-activity relationships and develop new therapeutic agents.
Chemical Biology Research
Employed as a tool compound in chemical biology for creating labelled peptides or probing biological systems. Its unique structure can confer specific properties useful in biochemical assays and studies.
Organic Synthesis
Acts as a versatile intermediate in multi-step organic syntheses. The functional groups present (carboxylic acid, protected amine) allow for diverse chemical transformations to build complex molecular architectures.
| Molecular weight | 384.26 |
|---|---|
| Empirical formula | C17H22BrNO4 |
| Assay | ≥96.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-α-(4-bromobenzyl)-DL-Pro-OH used for?
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This compound is used in chemical synthesis and peptide chemistry as a building block for creating modified peptides and complex organic molecules, particularly in medicinal chemistry and chemical biology research.
What are the CAS number and formula for Boc-α-(4-bromobenzyl)-DL-Pro-OH?
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The CAS number is 336817-91-5, and the empirical formula is C17H22BrNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-α-(4-bromobenzyl)-DL-Pro-OH with an assay of ≥96.0% (HPLC). This product is intended for research and laboratory use; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling considerations for this chemical?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a WGK Germany rating of 3, indicating it is hazardous to water.
How is Boc-α-(4-bromobenzyl)-DL-Pro-OH packed and shipped?
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Boc-α-(4-bromobenzyl)-DL-Pro-OH is carefully packed according to industry standards to ensure safe transit and is available for export globally.
How can I request a quote or sample?
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To request a quote or sample of Boc-α-(4-bromobenzyl)-DL-Pro-OH, please contact our sales team through the website or by phone, providing your contact details and the quantity required.
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