Boc-α-(2-propynyl)-L-proline
Boc-α-(2-propynyl)-L-proline (CAS 959578-39-3) is a heterocyclic building block with the molecular formula C13H19NO4 and a molecular weight of 253.29 g/mol. This protected unnatural amino acid derivative is utilised in asymmetric synthesis and peptide chemistry. Its chiral nature makes it valuable for creating stereochemically defined molecules in chemical biology and synthesis research. Offered by TSS, it is suitable for laboratory and research applications.
- IUPAC
- (R)-1-tert-Butoxycarbonyl-2-(2-propynyl)pyrrolidine-2-carboxylic acid,Boc-α-(2-propargyl)-L-proline,Boc-α-(2-propynyl)-Pro-OH
- Synonyms
- (R)-1-tert-Butoxycarbonyl-2-(2-propynyl)pyrrolidine-2-carboxylic acidBoc-α-(2-propargyl)-L-prolineBoc-α-(2-propynyl)-Pro-OH
Asymmetric Synthesis
Boc-α-(2-propynyl)-L-proline serves as a chiral building block for the enantioselective synthesis of complex molecules. Its specific stereochemistry is crucial for controlling the chirality of newly formed stereocenters in synthetic targets.
Peptide Chemistry
As an unnatural amino acid derivative, it can be incorporated into peptides to introduce unique structural features and functionalities. This is useful for developing peptidomimetics or modifying peptide properties for biochemical studies.
Chemical Biology
The compound's structure, featuring a protected proline core with an alkyne moiety, allows for its use in bioorthogonal chemistry and the synthesis of probes for studying biological systems. The alkyne can be utilized in click chemistry reactions.
Heterocyclic Compound Synthesis
It acts as a precursor for the construction of novel pyrrolidine-containing heterocyclic structures. These motifs are prevalent in many biologically active compounds and pharmaceuticals.
| Molecular weight | 253.29 |
|---|---|
| Empirical formula | C13H19NO4 |
| Assay | ≥96.5% (TLC)97% |
| Optical activity | [α]/D +97±2°, c = 1% in ethanol |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-α-(2-propynyl)-L-proline used for?
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Boc-α-(2-propynyl)-L-proline is primarily used as a chiral building block in asymmetric synthesis, peptide chemistry, chemical biology, and the synthesis of heterocyclic compounds. It is valuable for introducing specific stereochemistry and functionalities into target molecules.
What is the CAS number and formula for Boc-α-(2-propynyl)-L-proline?
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The CAS number for Boc-α-(2-propynyl)-L-proline is 959578-39-3, and its molecular formula is C13H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-α-(2-propynyl)-L-proline with a purity of ≥96.5% (TLC) or 97%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should Boc-α-(2-propynyl)-L-proline be handled and stored?
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Handle Boc-α-(2-propynyl)-L-proline with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. Store at 2-8°C to maintain its stability.
Is Boc-α-(2-propynyl)-L-proline a controlled substance?
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The provided data does not indicate that Boc-α-(2-propynyl)-L-proline is a controlled substance.
How is Boc-α-(2-propynyl)-L-proline shipped?
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Boc-α-(2-propynyl)-L-proline is typically packed for safe transport and exported globally by Tech Serve Solutions, adhering to relevant shipping regulations.
How can I request a sample or quote for Boc-α-(2-propynyl)-L-proline?
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To request a sample or a quote for Boc-α-(2-propynyl)-L-proline, please contact our sales team through the website or by phone.
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