Boc-α-(4-methylbenzyl)-DL-Pro-OH
Boc-α-(4-methylbenzyl)-DL-Pro-OH (CAS 351002-82-9) is a protected amino acid derivative with the molecular formula C18H25NO4 and a molecular weight of 319.40. This compound serves as a valuable building block in organic synthesis, particularly within the fields of chemical biology and peptide chemistry. Its structure, featuring a Boc-protected proline core with a 4-methylbenzyl substituent, enables specific modifications in complex molecule construction.
- IUPAC
- 1-Boc-2-(4-methylbenzyl)-2-pyrrolidinecarboxylic acid,Boc-α-(4-methylbenzyl)-DL-proline

Peptide Synthesis
Boc-α-(4-methylbenzyl)-DL-Pro-OH is employed as a modified amino acid residue in the synthesis of peptides. Its unique side chain can be incorporated to alter peptide structure, stability, or biological activity in research settings.
Chemical Synthesis
This compound is a versatile intermediate in multi-step organic synthesis. The Boc protecting group allows for controlled reactions at the amine nitrogen, facilitating the construction of complex organic molecules.
Chemical Biology Research
As an unnatural amino acid derivative, it finds application in probing biological pathways or developing novel biomolecules. Its incorporation can introduce specific structural features for studying protein-ligand interactions or enzyme mechanisms.
| Molecular weight | 319.40 |
|---|---|
| Empirical formula | C18H25NO4 |
| Assay | ≥96.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-α-(4-methylbenzyl)-DL-Pro-OH used for?
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Boc-α-(4-methylbenzyl)-DL-Pro-OH is primarily used as a building block in peptide synthesis, organic synthesis, and chemical biology research due to its unique proline derivative structure.
What are the CAS number and formula for Boc-α-(4-methylbenzyl)-DL-Pro-OH?
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The CAS number for Boc-α-(4-methylbenzyl)-DL-Pro-OH is 351002-82-9, and its molecular formula is C18H25NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-α-(4-methylbenzyl)-DL-Pro-OH with an assay of ≥96.0% by HPLC. This product is intended for research and laboratory use; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should Boc-α-(4-methylbenzyl)-DL-Pro-OH be handled?
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Handle Boc-α-(4-methylbenzyl)-DL-Pro-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Consult the Safety Data Sheet for detailed handling and hazard information.
Is Boc-α-(4-methylbenzyl)-DL-Pro-OH a controlled substance?
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Based on the provided data, there is no indication that Boc-α-(4-methylbenzyl)-DL-Pro-OH is a controlled substance.
How is Boc-α-(4-methylbenzyl)-DL-Pro-OH packed and shipped?
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TSS exports and ships chemical compounds globally. Specific packaging details are determined at the time of order fulfilment to ensure safe transport and compliance with shipping regulations.
How can I request a quote or sample for Boc-α-(4-methylbenzyl)-DL-Pro-OH?
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To request a quote or sample, please contact our sales team through the TSS website or by direct inquiry, providing the product name and CAS number (351002-82-9).
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