Boc-trans-4-hydroxy-L-prolinol
Boc-trans-4-hydroxy-L-prolinol (CAS: 61478-26-0), with the empirical formula C10H19NO4 and a molecular weight of 217.26 g/mol, is a chiral building block derived from the amino acid proline. It features a Boc-protected hydroxyl group and a prolinol moiety, making it valuable in synthetic organic chemistry. This compound serves as a key intermediate in the synthesis of complex molecules, particularly in peptide chemistry and the development of novel pharmaceuticals.

Peptide Synthesis
Used as a protected amino alcohol building block in solid-phase or solution-phase peptide synthesis, enabling the incorporation of specific structural features into peptide chains.
Chiral Synthesis
Serves as a chiral auxiliary or precursor in asymmetric synthesis, contributing to the stereoselective construction of complex organic molecules.
Pharmaceutical Intermediates
A key intermediate in the synthesis pathways for various active pharmaceutical ingredients (APIs) and drug candidates.
Chemical Biology Research
Employed in the design and synthesis of probes and modulators for biological systems, aiding in the study of biochemical pathways.
| Molecular weight | 217.26 |
|---|---|
| Empirical formula | C10H19NO4 |
| Assay | 96% |
| Optical activity | [α]20/D −47°, c = 1 in chloroform |
| Melting point | 81-86 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-trans-4-hydroxy-L-prolinol used for?
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Boc-trans-4-hydroxy-L-prolinol is primarily used as a chiral building block in peptide synthesis, asymmetric synthesis, and as an intermediate in the development of pharmaceuticals and in chemical biology research.
What are the CAS number and formula for Boc-trans-4-hydroxy-L-prolinol?
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The CAS number is 61478-26-0, and the empirical formula is C10H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-trans-4-hydroxy-L-prolinol with a minimum assay of 96%. This product is typically supplied for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should Boc-trans-4-hydroxy-L-prolinol be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet (SDS) for comprehensive handling and safety information.
Is this chemical exported internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Boc-trans-4-hydroxy-L-prolinol.
How can I request a quote or sample?
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Please contact our sales team through the website or by phone to request a quote or a sample of Boc-trans-4-hydroxy-L-prolinol.
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