Boc-propargyl-Gly-OH
Boc-propargyl-Gly-OH (CAS: 63039-48-5), a derivative of glycine, is a key building block in organic synthesis. With the molecular formula C10H15NO4 and a molecular weight of 213.23 g/mol, this compound features a protected amine and a terminal alkyne. Its structure makes it valuable in chemical biology and peptide chemistry for conjugation and modification reactions.
- IUPAC
- (S)-2-(Boc-amino)-4-pentynoic acid,Boc-L-2-propargylglycine,Boc-Pra-OH
- Synonyms
- (S)-2-(Boc-amino)-4-pentynoic acidBoc-L-2-propargylglycineBoc-Pra-OH
Organic Synthesis
This compound serves as a versatile building block in the synthesis of complex organic molecules. The presence of the Boc-protected amine and the terminal alkyne allows for orthogonal functionalisation in multi-step synthetic routes.
Chemical Biology
Boc-propargyl-Gly-OH is utilised in chemical biology for creating modified peptides or bioconjugates. The alkyne group is amenable to click chemistry reactions, enabling the attachment of biomolecules or labels.
Peptide Chemistry
As a functionalised amino acid derivative, it is employed in solid-phase and solution-phase peptide synthesis to introduce alkyne functionalities into peptide sequences for further derivatisation or study.
| Molecular weight | 213.23 |
|---|---|
| Empirical formula | C10H15NO4 |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]/D 26.0±2.0°, c = 1 in methanol |
| Storage temperature | −20°C |
Hazard statements
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-propargyl-Gly-OH used for?
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Boc-propargyl-Gly-OH is used as a building block in organic synthesis, chemical biology, and peptide chemistry, particularly for conjugation and modification reactions due to its protected amine and alkyne functionalities.
What are the CAS number and formula for Boc-propargyl-Gly-OH?
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The CAS number is 63039-48-5 and the empirical formula is C10H15NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-propargyl-Gly-OH with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Boc-propargyl-Gly-OH be handled safely?
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Handle Boc-propargyl-Gly-OH with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a respirator filter (type N95 or P1). It is classified as a GHS07 warning substance due to H317 (May cause an allergic skin reaction).
How is Boc-propargyl-Gly-OH packed and shipped?
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Boc-propargyl-Gly-OH is typically stored at -20°C. Specific packaging and shipping details for export are available upon request.
How can I request a sample or quote for Boc-propargyl-Gly-OH?
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To request a sample or obtain a quotation, please contact our sales department via the website or email, referencing the product name and CAS number.
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