Boc-pentafluoro-L-phenylalanine
Boc-pentafluoro-L-phenylalanine (CAS: 34702-60-8), with the empirical formula C14H14F5NO4 and a molecular weight of 355.26 g/mol, is a specialised unnatural amino acid derivative. Its structure incorporates a pentafluorophenyl group and a Boc protecting group, making it a valuable building block in chemical biology and advanced peptide synthesis. TSS supplies this compound for research and development purposes.
- IUPAC
- (S)-2-(Boc-amino)-3-(pentafluorophenyl)propionic acid
Peptide Synthesis
Utilised as a non-canonical amino acid to introduce fluorinated aromatic residues into peptide chains, altering their conformation, stability, and biological activity. The Boc protection facilitates controlled incorporation during solid-phase or solution-phase peptide synthesis.
Chemical Biology Research
Serves as a tool for investigating protein structure-function relationships and developing novel biomolecules. The unique electronic properties of the pentafluorophenyl ring can be exploited for biophysical studies and as a probe in biological systems.
Medicinal Chemistry
Incorporated into potential drug candidates to enhance metabolic stability, lipophilicity, or binding affinity. Fluorinated amino acids are increasingly important in the design of pharmaceuticals.
Materials Science
May be employed in the synthesis of specialised polymers or biomaterials where the properties of fluorinated aromatic groups are desired for specific functionalities.
| Molecular weight | 355.26 |
|---|---|
| Empirical formula | C14H14F5NO4 |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-pentafluoro-L-phenylalanine used for?
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Boc-pentafluoro-L-phenylalanine is primarily used in peptide synthesis and chemical biology research as a non-canonical amino acid to introduce fluorinated aromatic residues, modifying peptide properties for various applications including drug discovery and materials science.
What is the CAS number and formula for Boc-pentafluoro-L-phenylalanine?
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The CAS number for Boc-pentafluoro-L-phenylalanine is 34702-60-8, and its empirical formula is C14H14F5NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-pentafluoro-L-phenylalanine with an assay of ≥98.0% determined by HPLC. This is a research-grade chemical and is not represented as USP, EP, BP, or any other pharmacopoeia grade.
What are the safety and handling precautions for Boc-pentafluoro-L-phenylalanine?
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When handling Boc-pentafluoro-L-phenylalanine, it is essential to wear eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended. The chemical has a WGK Germany rating of 3, indicating it is hazardous.
How is Boc-pentafluoro-L-phenylalanine packed, shipped, and exported?
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Boc-pentafluoro-L-phenylalanine is carefully packed to ensure its integrity during transit. Tech Serve Solutions specialises in the global export of fine chemicals, adhering to all relevant shipping regulations.
How can I request a sample or quote for Boc-pentafluoro-L-phenylalanine?
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To request a sample or a quotation for Boc-pentafluoro-L-phenylalanine, please contact our sales department via the website or by phone, providing your details and the quantity required.
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