Boc-α-(1-naphthylmethyl)-DL-Pro-OH
Boc-α-(1-naphthylmethyl)-DL-Pro-OH (CAS: 351002-65-8) is a protected unnatural amino acid derivative with the molecular formula C21H25NO4 and a molecular weight of 355.43 g/mol. This compound serves as a valuable building block in organic synthesis, particularly within peptide chemistry and chemical biology research. Its unique structure makes it suitable for incorporating modified amino acid residues into peptides, enabling the exploration of novel biochemical properties and functions.
- IUPAC
- 1-Boc-2-(1-naphthylmethyl)-2-pyrrolidinecarboxylic acid,Boc-α-(1-naphthylmethyl)-DL-proline

Peptide Synthesis
Utilised as a modified proline derivative for the construction of unnatural peptides. It allows for the introduction of a naphthylmethyl side chain, influencing peptide conformation and receptor interactions.
Chemical Biology Research
Employed in the design and synthesis of peptides with specific biological activities. The unnatural amino acid can be incorporated to probe protein structure-function relationships or develop peptidomimetics.
Organic Synthesis Intermediate
Serves as a versatile intermediate for creating complex organic molecules. The Boc protecting group facilitates controlled coupling reactions in multi-step syntheses.
| Molecular weight | 355.43 |
|---|---|
| Empirical formula | C21H25NO4 |
| Assay | ≥96.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-α-(1-naphthylmethyl)-DL-Pro-OH used for?
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Boc-α-(1-naphthylmethyl)-DL-Pro-OH is primarily used as a building block in peptide synthesis, chemical biology research, and as an intermediate in organic synthesis for creating modified peptides and complex organic molecules.
What are the CAS number and formula for Boc-α-(1-naphthylmethyl)-DL-Pro-OH?
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The CAS number is 351002-65-8 and the molecular formula is C21H25NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-α-(1-naphthylmethyl)-DL-Pro-OH with an assay of ≥96.0% (HPLC). This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should Boc-α-(1-naphthylmethyl)-DL-Pro-OH be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for comprehensive handling information.
How is Boc-α-(1-naphthylmethyl)-DL-Pro-OH packed, shipped, and exported?
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Products are carefully packed according to industry standards to ensure safe transit and are available for global export. Specific packaging details can be provided upon request.
How can I request a sample or quote for Boc-α-(1-naphthylmethyl)-DL-Pro-OH?
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To request a sample or a quote, please contact our sales department through the website or by calling our customer service line.
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