(S)-α-Methoxy-2-naphthylacetic acid

CAS 157134-51-5C13H12O3Chemical Synthesis

(S)-α-Methoxy-2-naphthylacetic acid (CAS 157134-51-5, C13H12O3) is a chiral carboxylic acid with a molecular weight of 216.23. As a key chiral building block, it is primarily utilised in asymmetric synthesis and broader organic synthesis applications within research and development settings. Its specific stereochemistry makes it valuable for creating enantiomerically pure target molecules.

IUPAC: (S)-α-Methoxy-2-naphthaleneacetic acid,(S)-2-NMA

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(S)-α-Methoxy-2-naphthylacetic acid (C13H12O3) — chemical structure, CAS 157134-51-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisCarboxylic AcidsChemical SynthesisChiral Building BlocksOrganic Building Blocks

01 /Applications

Chiral Building Block in Organic Synthesis

This compound serves as a crucial starting material or intermediate in the stereoselective synthesis of complex organic molecules. Its defined chirality is leveraged to introduce specific stereocentres into target structures.

Asymmetric Synthesis

Utilised in reactions where the formation of a new chiral centre is controlled, leading to enantiomerically enriched products. It is a valuable tool for chemists aiming to synthesise single enantiomers.

Research and Development

Employed in academic and industrial research laboratories for exploring new synthetic routes and developing novel compounds. Its unique structural features are of interest in medicinal chemistry and materials science.

02 /Properties

Molecular weight	216.23
Empirical formula	C13H12O3
Assay	≥97.0% (HPLC)97%
Optical activity	[α]/D +177±5°, c = 0.1 in methanol
Optical purity	enantiomeric excess: ≥99% (HPLC)
Melting point	101-104 °C

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements

P301IF SWALLOWED

Protective equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

157134-51-5

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-α-Methoxy-2-naphthylacetic acid used for?

(S)-α-Methoxy-2-naphthylacetic acid is primarily used as a chiral building block in asymmetric synthesis and general organic synthesis for research and development purposes.

What is the CAS number and formula for (S)-α-Methoxy-2-naphthylacetic acid?

The CAS number is 157134-51-5 and the empirical formula is C13H12O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (S)-α-Methoxy-2-naphthylacetic acid with an assay of ≥97.0% (HPLC) and an optical purity of enantiomeric excess ≥99% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should (S)-α-Methoxy-2-naphthylacetic acid be handled safely?

This compound is classified as toxic if swallowed (H301) and requires careful handling. Use appropriate personal protective equipment including a dust mask (N95), eyeshields, face shields, and gloves. Ensure adequate ventilation.