(S)-α-Methyl-2-pyridinemethanol
(S)-α-Methyl-2-pyridinemethanol (CAS: 59042-90-9; C7H9NO; MW: 123.15 g/mol) is a chiral alcohol featuring a pyridine ring. This enantiomerically pure compound serves as a valuable building block in asymmetric synthesis and chemical manufacturing. Its specific stereochemistry makes it particularly useful for creating complex chiral molecules. The compound's optical activity is [α]/D -62±2.0°, with an enantiomeric ratio of ≥99.0:1.0.
- IUPAC
- (S)-1-(2-Pyridyl)ethanol,(S)-2-(1-Hydroxyethyl)pyridine
- Synonyms
- (S)-1-(2-Pyridyl)ethanol(S)-2-(1-Hydroxyethyl)pyridine

Asymmetric Synthesis
Utilised as a chiral building block in the stereoselective synthesis of complex organic molecules, including pharmaceuticals and agrochemicals. Its defined stereochemistry is crucial for controlling the chirality of target compounds.
Chiral Resolution Reagent
Can be employed in the separation of racemic mixtures into their individual enantiomers. Its specific chiral structure facilitates the selective interaction with one enantiomer over the other.
Heterocyclic Chemistry
Serves as a versatile intermediate for the synthesis of substituted pyridine derivatives. The presence of the hydroxymethyl group allows for further functionalisation and elaboration of the pyridine core.
| Molecular weight | 123.15 |
|---|---|
| Empirical formula | C7H9NO |
| Assay | ≥98.0% (GC) |
| Refractive index | n20/D 1.528 |
| Optical activity | [α]/D -62±2.0°, c = 1 in ethanol |
| Optical purity | enantiomeric ratio: ≥99.0:1.0 (GC) |
| Storage temperature | 2-8°C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-α-Methyl-2-pyridinemethanol used for?
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(S)-α-Methyl-2-pyridinemethanol is primarily used as a chiral building block in asymmetric synthesis and as a chiral resolution reagent.
What are the CAS number and formula for (S)-α-Methyl-2-pyridinemethanol?
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The CAS number is 59042-90-9 and the formula is C7H9NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-α-Methyl-2-pyridinemethanol with an assay of ≥98.0% (GC) and an enantiomeric ratio of ≥99.0:1.0. We do not represent this product as USP, BP, or EP grade.
How should (S)-α-Methyl-2-pyridinemethanol be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, face shields, and gloves. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash skin thoroughly after handling. It is harmful if swallowed and causes skin and eye irritation, and may cause respiratory irritation. Store at 2-8°C.
How is (S)-α-Methyl-2-pyridinemethanol packed and exported?
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(S)-α-Methyl-2-pyridinemethanol is carefully packed to ensure stability during transport and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for (S)-α-Methyl-2-pyridinemethanol?
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To request a sample or quote, please contact our sales team through the website or directly via email/phone.
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