(S)-α-Amino-γ-butyrolactone hydrochloride
(S)-α-Amino-γ-butyrolactone hydrochloride (CAS: 2185-03-7; Formula: C4H7NO2 · HCl) is a chiral building block with a molecular weight of 137.56 g/mol. It is a derivative of the unnatural amino acid homoserine, featuring a lactone ring structure. This compound finds utility in various chemical synthesis pathways, particularly in the development of peptides and unnatural amino acid derivatives. Its specific stereochemistry makes it valuable in stereoselective synthesis.
- IUPAC
- L-Homoserine lactone hydrochloride,HSI

Peptide Synthesis
Serves as a non-proteinogenic amino acid building block for incorporating modified residues into peptide chains, enabling the exploration of novel peptide structures and functions.
Chemical Synthesis
A versatile chiral intermediate utilised in organic synthesis for the construction of complex molecules where stereochemical control is essential.
Unnatural Amino Acid Research
Employed in the synthesis of unnatural amino acids, expanding the repertoire of amino acids available for biochemical and pharmaceutical research.
Chemical Biology
Investigated for potential applications in chemical biology as a tool for probing biological systems or developing novel bioactive compounds.
| Molecular weight | 137.56 |
|---|---|
| Empirical formula | C4H7NO2 · HCl |
| Assay | 97% |
| Optical activity | [α]20/D −27.8°, c = 1 in H2O |
| Melting point | 210-220 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-α-Amino-γ-butyrolactone hydrochloride used for?
+
(S)-α-Amino-γ-butyrolactone hydrochloride is primarily used as a chiral building block in peptide synthesis, chemical synthesis, and the research of unnatural amino acid derivatives and chemical biology applications.
What are the CAS number and formula for (S)-α-Amino-γ-butyrolactone hydrochloride?
+
The CAS number is 2185-03-7, and the formula is C4H7NO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (S)-α-Amino-γ-butyrolactone hydrochloride with an assay of 97%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should (S)-α-Amino-γ-butyrolactone hydrochloride be handled safely?
+
This compound is a warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
Is (S)-α-Amino-γ-butyrolactone hydrochloride available for export?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (S)-α-Amino-γ-butyrolactone hydrochloride.
How can I request a sample or quote for (S)-α-Amino-γ-butyrolactone hydrochloride?
+
To request a sample or quote, please contact our sales team through the website or by phone, providing the product name and CAS number.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis